Hydrochloric Acid → 4,4'-Dimethoxybibenzyl

HRID 979066

Reaktionsgleichung

Reaktionsgleichung von HRID 979066
[C:1]1([C:9]([CH2:11][C:12]2[CH:19]=[CH:18][C:15]([O:16][CH3:17])=[CH:14][CH:13]=2)=O)[CH:8]=[CH:7][C:4]([O:5][CH3:6])=[CH:3][CH:2]=1.O1CCOCC1.Cl>[Zn].C1(C)C=CC=CC=1>[CH3:17][O:16][C:15]1[CH:14]=[CH:13][C:12]([CH2:11][CH2:9][C:1]2[CH:2]=[CH:3][C:4]([O:5][CH3:6])=[CH:7][CH:8]=2)=[CH:19][CH:18]=1

Komponenten

6

Edukt 3

HCID 313Hydrochloric Acid2×HCID 312751,4-DioxaneHCID 67120Desoxyanisoin

Produkt 1

HCID 742614,4'-Dimethoxybibenzyl

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23994ZincKatalysatorHCID 1140TolueneLösungsmittel

Versuchsvorschrift

A mixture of 60 g of desoxyanisoin, 120 g of amalgamated zinc, 200 ml of dioxane, 100 ml of toluene and 200 ml of concentrated hydrochloric acid was refluxed for 24 hours. Another 50 ml of concentrated hydrochloric acid was added after the first 6 hours. The reaction mixture was cooled to room temperature and the organic layer was separated and mixed with 300 ml of ethyl acetate. It was washed with water, dried over anhydrous magnesium sulfate and concentrated to give 26 g of white waxy solid.

Aufarbeitung

  1. temperaturewas refluxed for 24 hours
  2. customthe organic layer was separated
  3. additionmixed with 300 ml of ethyl acetate
  4. washIt was washed with water
  5. dry with materialdried over anhydrous magnesium sulfate
  6. concentrationconcentrated
  7. customto give 26 g of white waxy solid

Quellen und Nachweise

ORD-Eintrag
ord-ad30e23285dd48ffb981e09dea068b82
Quelldatensatz
uspto-grants-1987_05
Patentnummer
US04666909

Verknüpfte Notizen

Wird geladen…