Water → 2,4-Dibenzyloxybenzyl Alcohol

HRID 981384Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 981384
[CH2:1]([O:8][C:9]1[CH:16]=[C:15]([O:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:14]=[CH:13][C:10]=1[CH:11]=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Na].O>CO>[CH2:1]([O:8][C:9]1[CH:16]=[C:15]([O:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:14]=[CH:13][C:10]=1[CH2:11][OH:12])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 18090802,4-Bis(benzyloxy)benzaldehydeHCID 5360545Sodium

Produkt 1

HCID 105677102,4-Dibenzyloxybenzyl AlcoholAusbeute 98,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

2,4-Dibenzyloxybenzaldehyde [V] (20 g) was dissolved in methanol (700 ml) and then, thereto was added sodium boronhydride (3.6 g) and this was left to stand at room temperature (20° C.) for 1.5 hours. To the reaction mixture was added water (1.5 liter) and the resulting precipitate was collected by filtration and recrystallized from ethanol to obtain 2,4-dibenzyloxybenzyl alcohol [VI] (19.8 g, yield 98%). Melting point: 84°-85° C.

Aufarbeitung

  1. waitthis was left
  2. customto stand at room temperature
  3. custom(20° C.)
  4. customfor 1.5 hours
  5. filtrationthe resulting precipitate was collected by filtration
  6. customrecrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-0b0474d1060844e798031de3275388c5
Quelldatensatz
uspto-grants-1991_02
Patentnummer
US04990614

Notizen zur Reaktion

Wird geladen…