Ethylamine → HCID 10334355, Verbindung

HRID 981909Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 981909
[CH2:1]([N:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8](Cl)=[C:7]([N+:16]([O-:18])=[O:17])[C:6]1=[O:19])[CH2:2][CH2:3][CH3:4].[CH2:20]([NH2:22])[CH3:21]>O1CCCC1>[CH2:1]([N:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]([NH:22][CH2:20][CH3:21])=[C:7]([N+:16]([O-:18])=[O:17])[C:6]1=[O:19])[CH2:2][CH2:3][CH3:4]

Komponenten

4

Edukt 2

HCID 6341EthylamineHCID 99709251-Butyl-4-chloro-3-nitroquinolin-2(1H)-one

Produkt 1

HCID 10334355HCID 10334355, VerbindungAusbeute 97 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

3.5 g (0.013 mole) of Compound d in Reference Example 4 was dissolved in 30 ml of tetrahydrofuran, and 8.0 ml (0.13 mole) of ethylamine was added with ice cooling, followed by stirring at room temperature overnight. The solvent was evaporated under reduced pressure and ice water was added to the residue. The precipitate was collected by filtration and dried, to afford 3.5 g of Compound e (97%).

Aufarbeitung

  1. customThe solvent was evaporated under reduced pressure and ice water
  2. additionwas added to the residue
  3. filtrationThe precipitate was collected by filtration
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-0a6203f950c24f5d95988075bf034413
Quelldatensatz
uspto-grants-1991_02
Patentnummer
US04994468

Notizen zur Reaktion

Wird geladen…