Benzene → 3,5,5-Trimethylhexanoylbenzene

HRID 983745

Reaktionsgleichung

Reaktionsgleichung von HRID 983745
[Cl-].[Al+3].[Cl-].[Cl-].[CH:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[CH3:11][CH:12]([CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH2:13][C:14](Cl)=[O:15]>O>[CH3:11][CH:12]([CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH2:13][C:14]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:15]

Komponenten

5

Edukt 3

HCID 241BenzeneHCID 1619293,5,5-Trimethylhexanoyl chlorideHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 222694783,5,5-Trimethylhexanoylbenzene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 143.4 grams of aluminum chloride and 351.6 grams of benzene was stirred at room temperature while 100 grams of 3,5,5-trimethylhexanoyl chloride was added to the reaction keeping the reaction temperature at approximately 35° C. over a period of 1.5 hours. The mixture was then stirred for 3 hours. The reaction mixture was poured into 500 grams of ice and stirred until all the ice dissolved. Water was added with cooling to give a homogenous mixture followed by extraction with 400 mL of ethyl acetate. The organic phase was washed with brine, dried with anhydrous magnesium sulfate and stripped to dryness to give 3,5,5-Trimethylhexanoylbenzene.

Aufarbeitung

  1. additionwas added to the reaction
  2. customat approximately 35° C.
  3. customof 1.5 hours
  4. dissolutiondissolved
  5. temperaturewith cooling
  6. customto give a homogenous mixture
  7. extractionfollowed by extraction with 400 mL of ethyl acetate
  8. washThe organic phase was washed with brine
  9. dry with materialdried with anhydrous magnesium sulfate

Quellen und Nachweise

ORD-Eintrag
ord-315d5ee2397343248fc0bd500add10bf
Quelldatensatz
uspto-grants-2005_03
Patentnummer
US06864396B2

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