3-Nonanone → 3-Nonanol

HRID 989728

Reaktionsgleichung

Reaktionsgleichung von HRID 989728
[CH3:1][CH2:2][C:3](=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[BH4-].[Na+]>CO>[CH3:1][CH2:2][CH:3]([OH:10])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

Komponenten

4

Edukt 2

HCID 612353-NonanoneHCID 4311764Sodium borohydride

Produkt 1

HCID 122163-NonanolAusbeute 96,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

20.5 g (144 mmol) of 3-nonanone are initially charged in 200 ml of methanol, 5.45 g (144 mmol) of sodium borohydride are added a little at a time at room temperature and the mixture is stirred overnight. The solvent is removed under reduced pressure and the mixture is then acidified and extracted with dichloromethane. The organic phase is dried over sodium sulphate. Removal of the solvent gives 20 g (96%) of a colourless oil.

Aufarbeitung

  1. customThe solvent is removed under reduced pressure
  2. extractionextracted with dichloromethane
  3. dry with materialThe organic phase is dried over sodium sulphate
  4. customRemoval of the solvent

Quellen und Nachweise

ORD-Eintrag
ord-f63b7042858a417da8139487ee5a4ea2
Quelldatensatz
uspto-grants-2002_10
Patentnummer
US06458796B1

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