Diethyl Ether → 2-Bromo-4-chlorobenzenediazonium tetrafluoroborate

HRID 992484

Reaktionsgleichung

Reaktionsgleichung von HRID 992484
[Br:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[NH2:4].[H+].[B-:11]([F:15])([F:14])([F:13])[F:12].[N:16]([O-])=O.[Na+].C(OCC)C>CCO>[F:12][B-:11]([F:15])([F:14])[F:13].[Br:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[N+:4]#[N:16]

Komponenten

6

Edukt 4

HCID 3283Diethyl EtherHCID 28118Tetrafluoroboric acidHCID 701102-Bromo-4-chloroanilineHCID 23668193Sodium Nitrite

Produkt 1

HCID 184127642-Bromo-4-chlorobenzenediazonium tetrafluoroborateAusbeute 96 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 2-bromo-4-chloroaniline (10.0 g, 48.4 mmol) and HBF4 in EtOH (60 mL) kept at 0° C. was treated with an aqueous solution (20 mL) of NaNO2 (3.34g, 48.4 mmol). After completion of the addition, diethyl ether (200 mL) was added to the mixture. The solid was collected by filtration, washed with water and dried under high vacuum affording the title compound (14.2 g, 96%) as white crystals.

Aufarbeitung

  1. customkept at 0° C.
  2. additionwas added to the mixture
  3. filtrationThe solid was collected by filtration
  4. washwashed with water
  5. customdried under high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-455616b784b7483eb55eb365e0f0b005
Quelldatensatz
uspto-grants-2002_10
Patentnummer
US06469042B1

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