Acetate → 5-(2,2-Difluoro-ethoxy)-7-chloro-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-one
Reaktionsgleichung
[Br:1][c:2]1[cH:3][c:4]2[c:8]([c:9]([Cl:11])[cH:10]1)[C:7](=[O:12])[N:6]([CH2:13][c:14]1[cH:15][cH:16][c:17]([O:20][C:21]([F:22])([F:23])[F:24])[cH:18][cH:19]1)[CH2:5]2.[C:25](=[O:26])([O-:27])[O-:28].[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[Cs+:29].[Cs+:30].[F:31][CH:32]([CH2:33][OH:34])[F:35].[O-:44][C:45]([CH3:46])=[O:47].[O-:48][C:49]([CH3:50])=[O:51].[Pd+2:43]>>[c:2]1([O:34][CH2:33][CH:32]([F:31])[F:35])[cH:3][c:4]2[c:8]([c:9]([Cl:11])[cH:10]1)[C:7](=[O:12])[N:6]([CH2:13][c:14]1[cH:15][cH:16][c:17]([O:20][C:21]([F:22])([F:23])[F:24])[cH:18][cH:19]1)[CH2:5]2
