Acryloylglycine

HCID 100321CAS 24599-25-5

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Basic information

Standard SMILES: C=CC(=O)NCC(=O)O
InChIKey: LZCXCXDOGAEFQX-UHFFFAOYSA-N
Molecular formula: C5H7NO3
Average molar mass: 129.11 g/mol
Monoisotopic mass: 129.04259308

Overview

N-Acryloylglycine is a N-acyl-amino acid.

Names & identifiers

Preferred name: Acryloylglycine
IUPAC: 2-(prop-2-enoylamino)acetic acid
English name: ACRYLAMIDO BUFFER
Molecular formula: C5H7NO3
Molecular weight: 129.11

Names & synonyms

acryloylglycine24599-25-51-Aminopropenal acetic acidRefChem:429447664-058-4N-Acryloylglycine2-(prop-2-enamido)acetic acid2-(prop-2-enoylamino)acetic acidAPAAAcryloyl Glycine2-acrylamidoacetic acidACRYLAMIDO BUFFER

Show more names

ACRYLAMIDO BUFFER PK 3.61-aminopropenalaceticacid

n-acryloyl glycineN-acryloyl-GlycineGlycine, N-(1-oxo-2-propen-1-yl)-N-Prop-2-enoylglycineMFCD00085223CHEBI:165890Glycine, N-(1-oxo-2-propenyl)-AKOS000186328

Database identifiers

CAS: 24599-25-5
PubChem CID: 100321
DTXSID: DTXSID50865161
ChEBI: CHEBI:165890
EC Number: 664-058-4
Nikkaji: J718.032B

Properties

Computed structural properties

XLogP: -0.3
Topological polar surface area: 66.4 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 3
Rotatable bonds: 3
Heavy atoms: 9
Formal charge: 0
Complexity: 141

Experimental & physicochemical properties

Physical DescriptionSolid

Physicochemical properties

Melting point: 132 · 132-136 °C
Boiling point: 399.7 · 399.7±34.0 °C(Predicted)
Density: 1.209 · 1.209±0.06 g/cm3(Predicted)
storage temp.: 2 · 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 3.66 · 3.66±0.10(Predicted)
form: solution
color: White to Off-White
Stability: Light Sensitive
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 302 · H302-H317-H319
Precautionary statements: 261 · P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Safety Statements: 22 · 22-24/25
WGK Germany: 3 · 3

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (97.4%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P333+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (97.4%)

Safety data

wgk: 3
Signal word: Warning
Symbol(GHS): GHS07
safety_code: 22-24/25
Hazard statements: H302-H317-H319
Precautionary statements: P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

Chemistry & industry

Pharmacology

Cellular LocationsCytoplasm

Applications · 1 item

UsesAcryloylglycine is a vinyl monomer containing an amido and carboxylic group that is used in various industries (pharmaceutical, food, cosmetic) as a synthetic intermediate. Acryloylglycine is also used in biology to preserve the integrity of microorganisms.