Barium acetate

HCID 10980

Basic information

CAS
543-80-6
Standard SMILES
CC(=O)[O-].CC(=O)[O-].[Ba+2]
InChIKey
ITHZDDVSAWDQPZ-UHFFFAOYSA-L
Molecular formula
C4H6BaO4
Average molar mass
255.41 g/mol
Monoisotopic mass
255.93185587

Overview

Barium acetate is an acetate salt in which the cationic component is barium(2+). It has a role as a catalyst and a mordant. It is an organic barium salt and an acetate salt.

Names & identifiers

Preferred name
Barium acetate
IUPAC
barium(2+) diacetate
English name
Barium acetate
Molecular formula
C4H6BaO4
Molecular weight
255.42

Names & synonyms

Barium acetate543-80-6Barium diacetateACETIC ACID, BARIUM SALTOctan barnatyAcetic Acid Barium Saltbarium(2+) diacetateCaswell No. 068ACCRIS 7240UNII-FBA31YJ60REINECS 208-849-0FBA31YJ60R
Show more names
octanbarnatyBariumAcetateGrBariumAcetateA.R.Bariumacetate,99%BARIUM ACETATE 99%BARIUM ACETATE XTLBARIUM ACETATE, ACS
NSC 75794barium(II) acetateBARYTA ACETICAAcetic acid barium salt (2:1)DTXSID7020130CHEBI:190441NSC-75794Dibarium diacetate

Database identifiers

CAS
543-80-6
PubChem CID
10980
DTXSID
DTXSID7020130
ChEBI
CHEBI:190441
UNII
FBA31YJ60R
EC Number
208-849-0
Nikkaji
J422G

Properties

Computed structural properties

Topological polar surface area
80.3 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
4
Rotatable bonds
0
Heavy atoms
9

Experimental & physicochemical properties

Chemical ClassesMetals -> Organic Acids, Metal Salts
Density · 2 items

2.47 g/cm³

2.468 @25 °C

SolubilitySolubility in water, g/100ml at 20 °C: 59
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description · 3 items

Dry Powder

White solid; [Hawley] White crystals, soluble in water; [MSDSonline]

WHITE CRYSTALS OR POWDER.

Physicochemical properties

Melting point
450 °C · 450°C
bulk density
1200 kg/m3 · 1200kg/m3
Density
2.46 · 2.46
vapor pressure
15.7 hPa · 15.7hPa at 25℃
storage temp.
5 °C · Store at +5°C to +30°C.
solubility
720 g/l · 720g/l

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 0.3% (1 of 287) of reports.

Warning

H302 (99.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P270, P271, P301+P317, P304+P340, P317, P330, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 287 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

Hazard information

Regulatory Information · 4 items

Chemical: Acetic acid, barium salt

Acetic acid, barium salt (2:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, barium salt (2:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 16-06-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/24153

Barium acetate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to human health
Fire HazardsNot combustible.
Hazards SummaryCan cause hypokalemia, cardiac arrhythmias, and muscular paralysis; [ICSC] Harmful by ingestion or inhalation; Oral LD50 (rat) = 921 mg/kg; [MSDSonline] See Barium.
EC ClassificationSymbol: Xn; R: 20/22; S: (2)-28; Note: A
UN ClassificationUN Hazard Class: 6.1; UN Pack Group: III

Safety & protection

Fire FightingIn case of fire in the surroundings, use appropriate extinguishing media.
First Aid Measures · 4 items

Fresh air, rest.

Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Refer for medical attention .

Safe StorageSeparated from strong oxidants, acids and food and feedstuffs.
Exposure Control and Personal Protection0.5 [mg/m3], as Ba, inhalable fraction(soluble compds)[German Research Foundation (DFG)]
Spillage Disposal · 1 item

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Eye PreventionWear safety spectacles.

Toxicology

TreatmentIntravenous infusion of potassium often relieves many of the symptoms of barium toxicity. (L214)
Health Effects · 1 item

The health effects of the different barium compounds depend on how well the compound dissolves in water or the stomach contents. At low doses, barium acts as a muscle stimulant, while higher doses affect the nervous system, causing cardiac irregularities, tremors, weakness, anxiety, dyspnea, paralysisand possibly death. Barium may also cause gastrointestinal disturbances, damage the kidneys and cause decreases in body weight. (L214)

Adverse EffectsACGIH Carcinogen - Not Classifiable.
Exposure Routes · 2 items

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Oral (L214) ; inhalation (L214)

Toxicity Summary · 1 item

Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to intracellular compartments. The intracellular translocation of potassium results in a decreased resting membrane potential, making the muscle fibers electrically unexcitable and causing paralysis. Some of these barium's effects may also be due to barium induced neuromuscular blockade and membrane depolarization. (L214)

Signs and Symptoms · 2 items

Abdominal pain. Diarrhoea. Nausea. Vomiting. Weakness. Shortness of breath.

Ingesting excess barium may cause vomiting, abdominal cramps, diarrhea, difficulties in breathing, increased or decreased blood pressure, numbness around the face, and muscle weakness. High levels may result in changes in heart rhythm or paralysis and possibly death. (L214)

Safety data

wgk
1
tsca
TSCA listed
rtecs
AF4550000
ridadr
1564
hs_code
2915 29 00
Toxicity
LD50 orally in Rabbit: 921 mg/kg

Chemistry & industry

Pharmacology

Metabolism/Metabolites · 1 item

Barium compounds are absorbed via ingestion and inhalation, the extent of which depends on the individual compound. In the body, the majority of the barium is found in the bone, while small amounts exists in the muscle, adipose, skin, and connective tissue. Barium is not metabolized in the body, but it may be transported or incorporated into complexes or tissues. Barium is excreted in the urine and faeces. (L214)

Uses & manufacturing

Uses · 3 items

Used as a chemical reagent; to make other acetates; as a textile mordant; in paint and varnish driers; [Hawley] Used as a lubricant and catalyst; [Merck Index]

Painting (Pigments, Binders, and Biocides) [Category: Paint]

Use (kg; approx.) in Germany (2009): >75000

U.S. Production2023: 352,736 lb
Consumer UsesCatalyst
Industry UsesCatalyst
General Manufacturing Information · 2 items

Not Known or Reasonably Ascertainable

Acetic acid, barium salt (2:1): ACTIVE

Applications · 5 items

DescriptionBarium acetate (Ba(C2H3O2)2) is the salt of barium (II) and acetic acid.

UsesBarium acetate [Ba(C2H3O2)2H2O], a white crystal, is used as a dryer for paints and varnishes. It is produced by adding acetic acid to barium sulfate and recovering the crystals by evaporation. It is also used as a textile mordant and catalyst.

UsesUsed as catalyst for organic reactions

UsesBarium acetate is used as a mordant for printing textile fabrics, for drying paints and varnishes and in lubricating oil. In chemistry, it is used in the preparation of other acetates; and as a catalyst in organic synthesis.

General DescriptionBarium acetate is the barium salt of acetic acid.

Preparation methods · 1 item

PreparationBarium acetate is generally produced by the reaction of acetic acid with barium carbonate : BaCO3 + 2 CH3COOH → (CH3COO)2Ba + CO2 + H2O The reaction is performed in solution and the barium acetate crystallizes out. Alternatively, barium sulfide can be used : BaS + 2 CH3COOH → (CH3COO)2Ba +H2S Again, the solvent is evaporated off and the barium acetate crystallized.

Suppliers103 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
阿诺西(上海)生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖北成丰化工有限公司13125175253 · [email protected]
廊坊乾耀科技有限公司0316-2617888 17301291189 · [email protected]

Additional notes

DefinitionChEBI: Barium acetate is an acetate salt in which the cationic component is barium(2+). It has a role as a mordant and a catalyst. It is an organic barium salt and an acetate salt.

Related reactions

7 records

Compound notes

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