Basic information
- CAS
37143-54-7- Standard SMILES
COCC(C)N- InChIKey
NXMXETCTWNXSFG-UHFFFAOYSA-N- Molecular formula
- C4H11NO
- Average molar mass
- 89.14 g/mol
- Monoisotopic mass
- 89.08406397
Overview
Methoxyisopropylamine appears as a colorless liquid,with a pungent, ammonia-like odor. Less dense than water. Vapors heavier than air. Contact may severely irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.
Names & identifiers
- Preferred name
- Methoxyisopropylamine
- IUPAC
- 1-methoxypropan-2-amine
- English name
- 1-Methoxy-2-propylamine
- Molecular formula
- C4H11NO
- Molecular weight
- 89.14
Names & synonyms
37143-54-71-Methoxy-2-propylamine2-Amino-1-methoxypropane1-Methoxy-2-propanamine2-Propanamine, 1-methoxy-DL-Alaninol methyl etherMethoxyisopropylamine1-Methyl-2-methoxyethylamine2-Methoxy-1-methylethylamineDTXSID402935935BQ7GUH18DTXCID609359
Show more names
1-methoxypropan-2-amineMOIPA2-Methoxy-1-Met2-METHOXYISOPROPYLAMMETHOXYISOPROPYLIMINE1-methoxy-2-propanamin2-METHOXYISOPROPYLAMINE
Ethylamine, 2-methoxy-1-methyl-EC 422-550-4EC 609-333-11-Methoxy-2-aminopropane1-MethoxyisopropylamineRefChem:8118152-AMINO-3-METHOXYPROPANEETHYLAMINE, 2-METHOXYMETHYL-
Database identifiers
- CAS
37143-54-7、49548-27-8- PubChem CID
- 123458
- DTXSID
DTXSID4029359- ChEMBL
CHEMBL3184692
Properties
Computed structural properties
- XLogP
- -0.4
- Topological polar surface area
- 35.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 6
- Formal charge
- 0
- Complexity
- 30.7
Experimental & physicochemical properties
Physical Description
Methoxyisopropylamine appears as a colorless liquid,with a pungent, ammonia-like odor. Less dense than water. Vapors heavier than air. Contact may severely irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.
Liquid
Physicochemical properties
- Boiling point
- 92.5 · 92.5-93.5 °C/743 mmHg (lit.)
- Density
- 0.845 g/mL · 0.845 g/mL at 25 °C (lit.)
- vapor pressure
- 38.4 · 38.4-50.54hPa at 20-25℃
- refractive index
- 20 · n20/D 1.4065(lit.)
- Flash point
- 48 °F · 48 °F
- storage temp.
- -20 °C · Storage temp. -20°C
- solubility
- Chloroform (Soluble), Methanol (Slightly)
- pka
- 8.84 · 8.84±0.10(Predicted)
- form
- Liquid
- Appearance
- Colorless to light yellow Liquid
Safety & regulation
GHS classification
GHS Classification
Danger
H225: Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P260, P264, P270, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P330, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P270, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)
Hazard information
Regulatory Information
2-Propanamine, 1-methoxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propanamine, 1-methoxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Status: Cease Manufacture Update: 10-11-2008 https://echa.europa.eu/registration-dossier/-/registered-dossier/4675
Status: Active Update: 28-10-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/7581
DOT LabelFlammable Liquid
Fire HazardsExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Health HazardsExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Reactive GroupAmines, Phosphines, and Pyridines
Reactivity AlertsHighly Flammable
Chemistry & industry
Uses & manufacturing
U.S. Production2023: 10,000,000 - <50,000,000 lb
Industry UsesIntermediate
General Manufacturing Information
All Other Basic Inorganic Chemical Manufacturing
2-Propanamine, 1-methoxy-: ACTIVE
Applications
Uses1-Methoxy-2-propylamine is used in the preparation of heterocyclic compounds, as integrase inhibiting antiviral agents.
Suppliers62 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
上海泰矶林实业有限公司02150630626 17717886015 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
北京索莱宝科技有限公司010-50973130 17801761073 · [email protected]
Hangzhou Sage Chemical Co., Ltd.+86057186818502 13588463833 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
重庆张邦医药科技有限责任公司028-84252981 18583719936 · [email protected]
Related reactions
104 records
Compound notes
Loading…