Methoxyisopropylamine → HCID 57851639, compound

HRID 77775

Reaction equation

HRID 77775 reaction equation
COCC(N[C:7]([C:9]1[CH:10]=[C:11]([C:24]2[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][CH:25]=2)[CH:12]=[C:13]([N:15]2[C:19]([C:20]([F:23])([F:22])[F:21])=[N:18][N:17]=[N:16]2)[CH:14]=1)=[O:8])C.C[O:32]CC(N)C>>[CH3:30][C:27]1[CH:26]=[CH:25][C:24]([C:11]2[CH:12]=[C:13]([N:15]3[C:19]([C:20]([F:23])([F:22])[F:21])=[N:18][N:17]=[N:16]3)[CH:14]=[C:9]([C:7]([OH:8])=[O:32])[CH:10]=2)=[CH:29][CH:28]=1

Participants

3

Reactant 2

HCID 123458MethoxyisopropylamineHCID 44600042HCID 44600042, compound

Product 1

HCID 57851639HCID 57851639, compound

Procedure

4′-Methyl-5-(5-trifluoromethyl-tetrazol-1-yl)-biphenyl-3-carboxylic acid (2-methoxy-1-methyl-ethyl)-amide was reacted with 2-methoxy-1-methyl-ethylamine using the procedure of step 4 of Example 3 to give 4′-methyl-5-(5-trifluoromethyl-tetrazol-1-yl)-biphenyl-3-carboxylic acid. MS (M+H)=420.

Sources & evidence

ORD record
ord-fa222cff1b8f410d91fea95db555e6cf
Source dataset
uspto-grants-2014_09
Patent number
US08841336B2

Linked notes

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