872-85-5O=Cc1ccncc1BGUWFUQJCDRPTL-UHFFFAOYSA-N872-85-5DTXSID1061237CHEMBL22516061025
1668
Danger
H314 (11.1%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation];H315 (88.9%): Causes skin irritation [Warning Skin corrosion/irritation];H317 (22.2%): May cause an allergic skin reaction [Warning Sensitization, Skin];H319 (85.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (83.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P260, P261, P264, P264+P265, P271, P272, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 54 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Status: Active Update: 27-07-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/10172
Isonicotinaldehyde: Does not have an individual approval but may be used under an appropriate group standard
Uses4-Pyridinecarboxaldehyde is an heterocyclic building block used for the synthesis of various pharmaceutical compounds, such as new 1,4-dihydropyridin-4-yl-phenoxyacetohydrazones, having anticonvulsant and anti-inflammatory properties.4-Pyridinecarboxaldehyde and some of its derivatives have also been reported as useful transamination reagents to introduce ketone or aldehyde groups onto the N-termini of antibodies for subsequent site-specifically conjugate aminooxy-functionalized molecules (including fluorescent dyes, polyethylene glycol, or porphyrins) to these entities. 4-Pyridinecarboxaldehyde can be used for the synthesis of: β-Unsaturated amides by coupling with N,N-disubstituted formamides; meso-Substituted A3-corroles; N-(4-pyridylmethyl)-L-valine as a ligand to construct zinc metal–organic frameworks (Zn-MOFs); 4′-Pyridyl terpyridines, with potential application as anticancer and antimicrobial agents; 4-pyridinecarboxaldehyde thiosemicarbazone, as a corrosion inhibitor for mild steel.
Uses4-Pyridinecarboxaldehyde, is an heterocyclic building block used for the synthesis of various pharmaceutical compounds, such as new 1,4-dihydropyridin-4-yl-phenoxyacetohydrazones, having anticonvulsant and anti-inflammatory properties.
Uses4-Pyridinecarboxaldehyde can be used for the synthesis of:γ,β-Unsaturated amides by coupling with N,N-disubstituted formamides.meso-Substituted A3-corroles.N-(4-pyridylmethyl)-L-valine as a ligand to construct zinc metal–organic frameworks (Zn-MOFs).4′-Pyridyl terpyridines, with potential application as anticancer and antimicrobial agents.4-pyridinecarboxaldehyde thiosemicarbazone, as a corrosion inhibitor for mild steel.
Preparation4-Pyridinecarbaldehyde is synthesized by oxidation of 4-picoline. The mixed gas of 4-picoline and air is passed through the vanadium-molybdenum catalyst layer heated to 400°C, and oxidized to generate 4-pyridinecarbaldehyde.
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7.1 [mg/m3]
78 [mg/m3]
470 [mg/m3]
Status: Active Update: 27-07-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/10172
Isonicotinaldehyde: Does not have an individual approval but may be used under an appropriate group standard