1,2-Epoxy-3-methoxypropane

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

...THEY ARE VERY IRRITATING TO EYES, SKIN, & RESPIRATORY TRACT. /GLYCIDYL ETHERS/

1,2-EPOXY-3-METHOXYPROPANE WAS MUTAGENIC IN KLEBSIELLA PNEUMONIAE.

TOPICAL APPLICATION OF 0.1 ML ALIQUOT OF 1,2-EPOXY-3-METHOXYPROPANE TO CLIPPED & DEPILATED BACKS OF GUINEA PIGS 4 TIMES IN 10 DAYS. AFTER 2 WK REST PERIOD, GUINEA PIGS WERE CHALLENGED ON THE CLIPPED FLANKS. TWO OF THE 49 GUINEA PIGS TESTED BECAME SENSITIZED.