Completing data — refresh the page later to see the latest
Basic information
- CAS
1867-65-8- Standard SMILES
Cl.c1csc(C2(N3CCCCC3)CCCCC2)c1- InChIKey
IIPLEZRBGQCZMF-UHFFFAOYSA-N- Molecular formula
- C15H24ClNS
- Average molar mass
- 285.884 g/mol
- Monoisotopic mass
- 285.13179845
Names & identifiers
- Preferred name
- Tenocyclidine hydrochloride (1:1)
- IUPAC
- 1-[1-(Thiophen-2-yl)cyclohexyl]piperidine--hydrogen chloride (1/1)
- English name
- CL-421
- Molecular formula
- C15H24ClNS
- Molecular weight
- 285.87576
Names & synonyms
GK 0CL-421ThienylcyclidineThienylphencyclidine1-[1-(2-Thienyl)cyclohexyl]piperidine Hydrochloride1-(1-thiophen-2-ylcyclohexyl)piperidine:hydrochloride
Database identifiers
- CAS
1867-65-8- PubChem CID
- 16640802
- DTXSID
DTXSID40904770- UNII
- 425WW340S2
- EC Number
- 631-590-3
Properties
Physicochemical properties
- Melting point
- 233 · 233-236 °C
- solubility
- 5 mg/ml; · DMF: 5 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 2 mg/ml; Ethanol: 2 mg/ml; Methanol: 1 mg/ml
- form
- A crystalline solid
- FDA UNII
- 425 WW340S2 · 425WW340S2
- Symbol(GHS)
- 7 · GHS07,GHS05
- Signal word
- Danger
- Hazard statements
- 318 · H318-H335-H315
- Precautionary statements
- 280 · P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Danger
- Symbol(GHS)
- GHS07,GHS05
- Hazard statements
- H318-H335-H315
- Precautionary statements
- P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
Chemistry & industry
Applications
DescriptionTenocyclidine (TCP), known more formally as N-[1-(2-thienyl)cyclohexyl] piperidine, is an analog of phencyclidine (PCP) in which the phenyl substituent is replaced with a thiophene group. TCP is a potent antagonist of the NMDA receptor-gated ion channel (Kd = 9 nM). TCP blocks NMDA-activated excitatory postsynaptic potential in brain more potently than PCP. PCP and many analogs, including TCP, block the uptake and enhance the release of dopamine both in vitro and in vivo. TCP is regulated as a Schedule I compound in the United States. This product is intended for forensic and research applications.
UsesAn analog of the hallucinogen Phencyclidine (P295500).
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…