1,4-Piperazinediethanesulfonic acid, potassium salt (1:2)

HCID 176078CAS 108321-27-3
Substructure searchFind similar structures

Basic information

Standard SMILES
O=S(=O)([O-])CCN1CCN(CCS(=O)(=O)[O-])CC1.[K+].[K+]
InChIKey
BJQYFCAMUXGZFN-UHFFFAOYSA-L
Molecular formula
C8H16K2N2O6S2
Average molar mass
378.6 g/mol
Monoisotopic mass
377.97239159

Names & identifiers

Preferred name
1,4-Piperazinediethanesulfonic acid, potassium salt (1:2)
IUPAC
dipotassium;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate
English name
Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt
Molecular formula
C8H19KN2O6S2
Molecular weight
342.47

Names & synonyms

108321-27-31,4-Piperazinediethanesulfonic acid, dipotassium saltDTXSID90730421,4-Piperazinediethanesulfonic acid, potassium salt (1:2)RefChem:73380DTXCID1033111PIPES dipotassium saltPotassium 2,2'-(piperazine-1,4-diyl)diethanesulfonateMFCD00069751Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium saltdipotassium 2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonatePiperazine-1,4-bis(2-ethanesulfonic acid ) dipotassium salt
Show more names
PIPES DIPOTASSIUMPIPES 2KPIPES-K2METHYLCELLULOSE 4000 CPPIPES DIPOTASSIUM SALT, VETECPIPES dipotassiuM salt (PIPES-K{2})PIPES dipotassium salt, 99%, for bioPIPES dipotassium salt (PIPES-K2), BCPIPESDIPOTASSIUMSALT,BIOLOGICALBUFFER
dipotassium;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonatePiperazine-N,N/'-bis-(2-ethanesulphonic acid) dipotassium saltdipotassium 2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethane-1-sulfonateBJQYFCAMUXGZFN-UHFFFAOYSA-LPiperazine-1,4-bis(2-ethanesulfonic acid) dipotassium saltSCHEMBL9897196C8H16K2N2O6S2Piperazine-N,N'-bis-(2-ethanesulphonic acid)dipotassium salt

Database identifiers

CAS
108321-27-3
PubChem CID
176078
DTXSID
DTXSID9073042

Properties

Computed structural properties

Topological polar surface area
138 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
8
Rotatable bonds
4
Heavy atoms
20

Experimental & physicochemical properties

Chemical ClassesOther Uses -> Biological Buffers
Physical DescriptionWhite solid; [Sigma-Aldrich MSDS]

Physicochemical properties

storage temp.
Store at RT.
solubility
2 O: · H2O: 0.5 g/mL, clear, colorless
form
crystalline powder
PH
6.1 · 6.1-7.5
pka
6.8 · 6.8(at 25℃)
PH Range
6.1 · 6.1 - 7.5

Safety & regulation

Hazard information

Regulatory InformationPMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Hazards SummaryNot considered hazardous by GHS classification; [Sigma-Aldrich MSDS] See PIPES.

Safety data

F
10
PPE
Eyeshields, Gloves, type N95 (US)
wgk
3
tsca
TSCA listed
hs_code
29335995
risk_code
36/37/38

Chemistry & industry

Uses & manufacturing

General Manufacturing Information1,4-Piperazinediethanesulfonic acid, potassium salt (1:2): ACTIVE
Applications · 2 items

UsesPIPES (1,4-Piperazinediethanesulfonic acid) dipotassium salt has been used as buffer for fluorescence polarization microscopy studies of kinesin-microtubule binding. It is suitable for use as a component of PHEM buffer ([K-PIPES], HEPES, EGTA, and MgSO4) used during rinsing and blocking steps in immunofluorescence imaging of HeLa cells. It is also suitable for use as buffer for purification of tubulin.

General DescriptionPIPES (1,4-Piperazinediethanesulfonic acid) is a zwitterionic buffer. It is a stable buffer and is used majorly in fixation solutions. PIPES is inert towards enzymatic and non-enzymatic reactions. However, it generates artefacts in transmission electron microscope imaging.

Suppliers50 total

常州帝通化工有限公司+86-0519-88298848 · [email protected]
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
广州纳珑化工有限公司13192879270; 13192879270 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

Related reactions

1 records
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