HCID 87452564, compound → HCID 151299716, compound

HRID 1105489

Reaction equation

HRID 1105489 reaction equation
C#CC(O)(CO)CO>O.O.O.O.O.O=S(=O)([O-])[O-].[Cu+2].O=S(=O)([O-])CCN1CCN(CCS(=O)(=O)[O-])CC1.[K+].[K+].O.O.O.O>C#C[C@](O)(C=O)CO

Participants

5

Reactant 1

HCID 87452564HCID 87452564, compound

Product 1

HCID 151299716HCID 151299716, compoundYield 68%

Reagents, catalysts & solvents 3

HCID 24463Copper sulfate pentahydrateReagentHCID 1760781,4-Piperazinediethanesulfonic acid, potassium salt (1:2)ReagentHCID 962WaterSolvent4×

Conditions

Temperature
25 °C
pH
7.5
Other
aeration began after addition of copper_sulfate

Sources & evidence

ORD record
ord-9b830b3dea9b4c68b349f901df69e119
Source dataset
synthesis of islatravir by biocatalytic cascade
Original link
View source

Linked notes

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