CAS 7646-67-5 N-(2-Hydroxyethyl)acrylamide (stabilized with MEHQ) (HCID 193628)

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Basic information

CAS: 7646-67-5
Standard SMILES: C=CC(=O)NCCO
InChIKey: UUORTJUPDJJXST-UHFFFAOYSA-N
Molecular formula: C5H9NO2
Average molar mass: 115.13 g/mol
Monoisotopic mass: 115.06332853

Overview

See also: (2-Hydroxyethyl)acrylamide (annotation moved to).

Names & identifiers

Preferred name: N-(2-Hydroxyethyl)acrylamide (stabilized with MEHQ)
IUPAC: N-(2-hydroxyethyl)prop-2-enamide
English name: N-(2-Hydroxyethyl)acrylamide, HEAA
Molecular formula: C5H9NO2
Molecular weight: 115.13

Names & synonyms

N-(2-hydroxyethyl)prop-2-enamideN-(2-HYDROXYETHYL)ACRYLAMIDE (STABILIZED WITH MEHQ)RefChem:825485619-814-8700-169-7N-(2-Hydroxyethyl)acrylamide7646-67-5MFCD11110645n-hydroxyethylacrylamideN-2-hydroxyethylacrylamideSCHEMBL14966CH2=CH(CO)NHCH2CH2OH

Show more names

N-HydroxyethyLN-EthylolacrylamideN-Ethanolacrylamide(2-Hydroxyethyl)acrylamide2-Propenamide, N-(2-hydroxyethyl)-

SCHEMBL13341773N-(2-Hydroxyethyl)-2-propenamideN-Hydroxyethyl acrylamideAS-59388D78367EN300-103180N-(2-Hydroxyethyl)acrylamide, (stabilized with MEHQ)HEAA

Database identifiers

CAS: 7646-67-5
PubChem CID: 193628
DTXSID: DTXSID80997843
EC Number: 619-814-8、700-169-7
Nikkaji: J38.878E

Properties

Computed structural properties

XLogP: -0.6
Topological polar surface area: 49.3 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 2
Rotatable bonds: 3
Heavy atoms: 8
Formal charge: 0
Complexity: 90.4

Physicochemical properties

Boiling point: 129 · 129-130 °C
Density: 1.111 g/mL · 1.111 g/mL at 25 °C
vapor pressure: 0.021 Pa · 0.021Pa at 25℃
refractive index: 20 · n20/D 1.505
Flash point: 110 °C · 110 °C
storage temp.: 2 · 2-8°C
Water Solubility: Soluble in water
pka: 14.1 · 14.10±0.46(Predicted)
form: liquid
color: Colorless to Light yellow to Light orange
Cosmetics Ingredients Functions: BINDING
InChI: InChI=1S/C5H9NO2/c1-2-5(8)6-3-4-7/h2,7H,1,3-4H2,(H,6,8)
InChIKey: UUORTJUPDJJXST-UHFFFAOYSA-N
SMILES: C(NCCO)(=O)C=C
LogP: -0.73 at · -0.73 at 20℃ and pH7
Surface tension: 72 mN/m · 72mN/m at 1g/L and 20℃

Safety & regulation

GHS classification

GHS Classification · 6 items

Danger

H318 (97.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P260, P264+P265, P280, P305+P354+P338, P317, P319, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

Hazard information

Regulatory InformationStatus: Active Update: 15-12-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/33694

Hazard Classes and Categories · 2 items

Eye Dam. 1 (100%)

Eye Dam. 1 (97.9%)

Safety data

PPE: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 1
hs_code: 29241990
risk_code: 22-36/37/38-48/22-41
Signal word: Danger
Symbol(GHS): GHS05,GHS08
hazard_code: Xn
safety_code: 26-39
Storage Class: 10 - Combustible liquids
Hazard statements: H318-H373
REACH Registrations: Active
Hazard Classifications: Eye Dam. 1STOT RE 2 Oral
Precautionary statements

Chemistry & industry

Applications · 1 item

UsesN-Hydroxyethyl acrylamide is an amphipathic polymer that can be used for a variety of applications such as:preparation of hydrogels for the formation of a stimulo-responsive polymer for cell signaling and bioengineering researchin the synthesis of lanthanide based luminescent materials for sensors and bio-imagingformation of adhesive hydrogel for potential usage in the smart adhesives