Sodium Phosphate, Monobasic, Dihydrate (HCID 23673460)

Overview

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Names & identifiers

Preferred name: Sodium Phosphate, Monobasic, Dihydrate
IUPAC: sodium;dihydrogen phosphate;dihydrate
English name: Sodium dihydrogen phosphate dihydrate
Molecular formula: NaH2PO4·2H2O
Molecular weight: 156.01

Names & synonyms

13472-35-0Sodium dihydrogen phosphate dihydrateSodium phosphate monobasic dihydrateMonosodium phosphate dihydrateSodium phosphate, monobasic, dihydratePhosphoric acid, monosodium salt, dihydrateSodium phosphate dihydrateMonosodium dihydrogen phosphate dihydrateSodium phosphate (NaH2PO4) dihydrateUNII-5QWK6659565QWK665956DTXSID90158903

Show more names

Sodium dihydrogen orthophosphateSODIUM BIPHOSPHATESODIUM DIHYDROGEN PHOSPHATE 2H2OKH2PO7NaH?PO?·2H?OSAMARIUM 1,000PPM99.0 ~ 101.0%，ACS

Sodium Dihydrogen Orthophosphate dihydrateMONOBASIC SODIUM PHOSPHATE DIHYDRATEMONOBASIC SODIUM PHOSPHATE, DIHYDRATESODIUM PHOSPHATE MONOBASIC (DIHYDRATE)MONOSODIUM DIHYDROGEN PHOSPHATE, DIHYDRATESODIUM PHOSPHATE, MONOBASIC, DIHYDRATE [II]SODIUM PHOSPHATE, MONOBASIC, DIHYDRATE [MI]SODIUM PHOSPHATE MONOBASIC (DIHYDRATE) [WHO-DD]

Database identifiers

CAS: 13472-35-0
PubChem CID: 23673460
DTXSID: DTXSID90158903
UNII: 5QWK665956
EC Number: 603-853-2

Properties

Computed structural properties

Topological polar surface area: 82.6 Å²
Hydrogen bond donors: 4
Hydrogen bond acceptors: 6
Rotatable bonds: 0
Heavy atoms: 8
Formal charge: 0
Complexity: 61.9

Experimental & physicochemical properties

Chemical ClassesMetals -> Phosphates, Metallic Salts

Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List

Physical DescriptionColorless solid; [Merck Index] White hygroscopic solid; [Acros Organics MSDS]

Physicochemical properties

Melting point: 60 °C · 60 °C
Density: 1 · 1,915 g/cm3
bulk density: 1000 kg/m3 · 1000kg/m3
storage temp.: 5 °C · Store at +5°C to +30°C.
solubility: 2 O: · H2O: 1 M at 20 °C, clear, colorless
form: Solid
color: White
Odor: Odorless
PH Range: 4.2 · 4.2 - 4.5
PH: 4 · 4.0-4.5 (25℃, 50mg/mL in H2O)
Water Solubility: SOLUBLE
Sensitive: Hygroscopic
λmax: 260 nm · λ: 260 nm Amax: 0.085λ: 280 nm Amax: 0.070
Merck: 14 · 14,8660
Stability: Stable.
Cosmetics Ingredients Functions: BUFFERINGDEODORANTANTI-SEBORRHEIC
InChI: 1S/Na.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+1;;;/p-1
InChIKey: VBJGJHBYWREJQD-UHFFFAOYSA-M
SMILES: O.O.[Na+].OP(O)([O-])=O || O.O.[Na+].OP(O)([O-])=O
FDA 21 CFR: 172.892 · 172.892
CAS DataBase Reference: 13472 · 13472-35-0(CAS DataBase Reference)
EWG's Food Scores: 1 · 1
FDA UNII: 5 QWK665956 · 5QWK665956
EPA Substance Registry System: Phosphoric acid, monosodium salt (13472-35-0)
UNSPSC Code: 12352302 · 12352302
NACRES: 25 · NA.25
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 302 · H302-H315-H319-H335
Precautionary statements: 261 · P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Hazard Codes: Xi
Risk Statements: 36 · 36-36/37/38
Safety Statements: 39 · 39-26-24/25-36
WGK Germany: 1 · 1
RTECS: 1900500 · WA1900500
TSCA: Yes
HS Code: 2835 · 2835 22 00
Storage Class: 11 · 11 - Combustible Solids
Toxicity: 50 orally · LD50 orally in Rabbit: 8290 mg/kg LD50 dermal Rabbit > 7940 mg/kg

Safety & regulation

GHS classification

GHS Classification · 3 items

This chemical does not meet GHS hazard criteria for 100% (52 of 52) of all reports.

Not Classified

Aggregated GHS information provided per 52 reports by companies from 2 notifications to the ECHA C&L Inventory.

Hazard information

Regulatory Information · 2 items

Chemical: Phosphoric acid, monosodium salt, dihydrate

Sodium phosphate, monobasic, dihydrate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Phosphoric acid, monosodium salt, dihydrate: Human health tier I assessment

Hazards SummaryIntraperitoneal LD50 (mouse) > 5,008 mg/kg; [RTECS] An eye irritant; [Acros Organics MSDS] See Sodium phosphate, monobasic.

Hazard Classes and CategoriesNot Classified

Safety data

wgk: 1
tsca: Yes
rtecs: WA1900500
hs_code: 2835 22 00
Toxicity: LD50 orally in Rabbit: 8290 mg/kg LD50 dermal Rabbit > 7940 mg/kg
risk_code: 36-36/37/38
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi
safety_code: 39-26-24/25-36
Storage Class: 11 - Combustible Solids
Hazard statements: H302-H315-H319-H335
Precautionary statements: P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Chemistry & industry

Uses & manufacturing

UsesUsed in boiler water treatment, food production (dry acidulant and sequestrant), and human and veterinary medicine (urinary acidifier); [Merck Index]

Applications · 3 items

DescriptionSodium Dihydrogen Phosphate occurs as two forms: the crystal form (dihydrate) called Sodium Dihydrogen Phosphate (crystal) and anhydrous form called Sodium Dihydrogen Phosphate (anhydrous) It is used as an acidity regulator and sequestrant in foods. It is used as a pH buffer (baking powders, fleet enema solution, electroplating baths, and acid cleaners), emulsifier, laboratory reagent, metal phosphating reagent, and textile dyeing/printing auxiliary. It is also used to treat boiled water and waste waster and to remove halogen from waste gases. Furthermore, it is used as a cattle feed supplement, as nutritional supplement in food, in dentrifice formulations, in vitreous enamel frits, for the synthesis of pharmaceuticals, and as a phosphate source for micro-organisms in effluent treatment.

UsesSodium dihydrogen phosphate dihydrate acts as buffering capacity reagent in molecular biology, biochemistry and chromatography. It is used in the preparation of biological buffers. It is also used in the purification of antibodies, as a laxative and, in combination with other sodium phosphates.Sodium phosphate monobasic dihydrate is a reagent with very high buffering capacity widely used in molecular biology, biochemistry and chromatography. Sodium phosphate dibasic is highly hygroscopic and water soluble.Recommended chemicals for the preparation of phosphate buffers are sodium dihydrogen phosphate dihydrate，NaH2PO4.2H2O(mol. wt.156.0)，disodium hydrogen phosphate dihydrate，Na2HPO4.2H2O (mol. wt.178.0), and sodium hydroxide pellets.

UsesSodium dihydrogen phosphate dihydrate is typically used as a phosphate buffer system component for downstream biomolecule chromatography steps or final liquid formulation.Due to its low microbial and endotoxin limits, Sodium dihydrogen phosphate dihydrate Emprove Expert is especially suitable for high-risk applications.