Bis(2-Methoxyethyl)amine (HCID 2383)

Overview

structure

Names & identifiers

Preferred name: Bis(2-Methoxyethyl)amine
IUPAC: 2-methoxy-N-(2-methoxyethyl)ethanamine
English name: Bis(2-methoxyethyl)amine
Molecular formula: C6H15NO2
Molecular weight: 133.19

Names & synonyms

Bis(2-Methoxyethyl)amine111-95-52-Methoxy-N-(2-methoxyethyl)ethanamineDimethoxyethylamineEthanamine, 2-methoxy-N-(2-methoxyethyl)-DTXSID4059411RefChem:134193DTXCID0033207203-923-92,2'-DimethoxydiethylamineBis(methoxyethyl)amineBis-(2-methoxyethyl)-amine

Show more names

NSC 78431Bis(2-Methoxyethyl)aMine 98%Bis(2-methoxyethyl)amine, 98+%BIS(2-METHOXYETHYL)AMINE USP/EP/BP2-Methoxy-N-(2-methoxyethyl)-ethanam2-methoxy-n-(2-methoxyethyl)-ethanamin2-methoxy-N-(2-methoxyethyl)-Ethanamine

MFCD00025906N,N-bis(2-methoxyethyl)amineDiethylamine, 2,2'-dimethoxy-NSC-784312-Methoxy-N-(2-methoxyethyl)ethanamine; 2,2'-Dimethoxydiethylamine; Bis(2-methoxyethyl)amine; Di(2-methoxyethyl)amine; N,N-Bis(2-methoxyethyl)amine; NSC 78431Di-(2-methoxyethyl)amineBis(2-methoxyethyl);aminebismethoxyethylamine

Database identifiers

CAS: 111-95-5
PubChem CID: 2383
DTXSID: DTXSID4059411
UNII: UEJ75Q8JL5
EC Number: 203-923-9
Nikkaji: J193.599B

Properties

Computed structural properties

XLogP: -0.5
Topological polar surface area: 30.5 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 3
Rotatable bonds: 6
Heavy atoms: 9
Formal charge: 0
Complexity: 44.3

Physicochemical properties

Melting point: -60 °C · <-60°C
Boiling point: 170 · 170-172 °C(lit.)
Density: 0.902 g/mL · 0.902 g/mL at 25 °C(lit.)
refractive index: 20 · n20/D 1.419(lit.)
Flash point: 137 °F · 137 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
Water Solubility: Completely miscible in water
form: clear liquid
pka: 8.67 · 8.67±0.19(Predicted)
color: Colorless to Light orange to Yellow
BRN: 1736313 · 1736313
Henry's Law Constant: 1.1 · 1.1×102 mol/(m3Pa) at 25℃, Du et al. (2017)
InChI: 1S/C6H15NO2/c1-8-5-3-7-4-6-9-2/h7H,3-6H2,1-2H3
InChIKey: IBZKBSXREAQDTO-UHFFFAOYSA-N
SMILES: COCCNCCOC
LogP: -0.373 · -0.373 (est)
CAS DataBase Reference: 111 · 111-95-5(CAS DataBase Reference)
EPA Substance Registry System: 2 · Ethanamine, 2-methoxy-N-(2-methoxyethyl)- (111-95-5)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02,GHS05,GHS07
Signal word: Danger
Hazard statements: 226 · H226-H312-H314
Precautionary statements: 210 · P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: C
Risk Statements: 34 · 34
Safety Statements: 26 · 26-36/37/39-45
RIDADR: 2734 · UN 2734 8/PG 2
WGK Germany: 3 · 3
F: 34 · 34
TSCA: TSCA listed
HazardClass: 8 · 8
PackingGroup: II
HS Code: 29221990 · 29221990
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 4 DermalEye · Acute Tox. 4 DermalEye Dam. 1Flam. Liq. 3Skin Corr. 1B

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 75 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesFlam. Liq. 3 (100%)

Safety data

F: 34
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 3
tsca: TSCA listed
ridadr: UN 2734 8/PG 2
hs_code: 29221990
risk_code: 34
Signal word: Danger
Symbol(GHS): GHS02,GHS05,GHS07
hazard_code: C
safety_code: 26-36/37/39-45
hazard_class: 8
Storage Class: 3 - Flammable liquids
packing_group: II
Hazard statements: H226-H312-H314
Hazard Classifications: Acute Tox. 4 DermalEye Dam. 1Flam. Liq. 3Skin Corr. 1B
Precautionary statements: P210-P233-P240-P280-P303+P361+P353-P305+P351+P338

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationEthanamine, 2-methoxy-N-(2-methoxyethyl)-: ACTIVE

Applications · 1 item

UsesBis(2-methoxyethyl)amine is used to prepare pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of cyclin-dependent kinases 4 and 6. It is also used to synthesize (pyridyl)pyrazolopyrimidines as corticotropin-releasing factor receptor antagonists.