CAS 19686-73-8 1-Bromo-2-propanol (HCID 29740)

Overview

1-bromo-2-propanol is a colorless to dark brown liquid. (NTP, 1992)

Names & identifiers

Preferred name: 1-Bromo-2-propanol
IUPAC: 1-bromopropan-2-ol
English name: 1-BROMO-2-PROPANOL
Molecular formula: C3H7BrO
Molecular weight: 138.99

Names & synonyms

1-Bromopropan-2-ol1-BROMO-2-PROPANOL19686-73-82-Propanol, 1-bromo-Propylene bromohydrin2-Hydroxypropyl bromide1-Bromo-2-hydroxypropaneMFCD000045292-hydroxybromopropane2-Hydroxy-2-methylethyl bromide1-bromo-propan-2-ol7DGL334X4W

Show more names

79.0%(GC)1-bromo-2-propano1-BROMOPROPANOL-2Glycerol Impurity 1302-hydroxypropylbromide

CCRIS 5978(R)-1-Bromo-2-propanolEINECS 243-225-1BRN 1071195UNII-7DGL334X4W2-hydroxy propyl bromideracemic 1-bromo-2-propanol61951-89-1

Database identifiers

CAS: 19686-73-8、61951-89-1
PubChem CID: 29740
DTXSID: DTXSID8024656
ChEBI: CHEBI:144331
UNII: 7DGL334X4W
EC Number: 243-225-1、612-812-8
Nikkaji: J3.458D

Properties

Computed structural properties

XLogP: 0.7
Topological polar surface area: 20.2 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 1
Rotatable bonds: 1
Heavy atoms: 5
Formal charge: 0
Complexity: 22.9

Experimental & physicochemical properties

Chemical ClassesOther Classes -> Halogenated Alcohols

SpringerMaterials PropertiesOptical coefficient

Density1.5585 at 86 °F (NTP, 1992) - Denser than water; will sink

Solubilitygreater than or equal to 100 mg/mL at 72 °F (NTP, 1992)

Flash Point · 2 items

130 °F (NTP, 1992)

130 °F

Boiling Point293 to 298 °F at 760 mmHg (NTP, 1992)

Physicochemical properties

Boiling point: 145 · 145-148 °C (lit.)
Density: 1.53 g/mL · 1.53 g/mL at 25 °C (lit.)
refractive index: 20 · n20/D 1.480(lit.)
Flash point: 130 °F · 130 °F
storage temp.: 2 · Inert atmosphere,2-8°C
form: Liquid
pka: 13.89 · 13.89±0.20(Predicted)
color: Clear colorless to brown
BRN: 1071195 · 1071195
Stability: Stable. Combustible. Incompatible with strong oxidizing agents. May be light sensitive.
InChI: 1S/C3H7BrO/c1-3(5)2-4/h3,5H,2H2,1H3
InChIKey: WEGOLYBUWCMMMY-UHFFFAOYSA-N
SMILES: CC(O)CBr
CAS DataBase Reference: 19686 · 19686-73-8(CAS DataBase Reference)
FDA UNII: 7 DGL334X4W · 7DGL334X4W
EPA Substance Registry System: 1 · 1-Bromo-2-propanol (19686-73-8)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02,GHS07
Signal word: Warning
Hazard statements: 226 · H226-H315-H319
Precautionary statements: 210 · P210-P233-P240-P241-P303+P361+P353-P305+P351+P338
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: C
Risk Statements: 10 · 10-34
Safety Statements: 26 · 26-36/37/39-45
RIDADR: 2920 · UN 2920 8/PG 2
WGK Germany: 3 · 3
RTECS: 7388000 · UA7388000
TSCA: TSCA listed
HazardClass: 3.2 · 3.2
PackingGroup: III
HS Code: 29055998 · 29055998
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 2 Flam · Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2
Limited Quantities: 1 L · 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 100% (57 of 57) of all reports.

Not Classified

Aggregated GHS information provided per 57 reports by companies from 1 notifications to the ECHA C&L Inventory.

Danger

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)

Hazard information

Regulatory Information · 2 items

Chemical: C.I. Solvent Violet 36

C.I. Solvent Violet 36: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

DOT LabelFlammable Liquid

Fire HazardsThis chemical is combustible. (NTP, 1992)

Health Hazards · 1 item

SYMPTOMS: Symptoms of exposure to this compound may include eye and skin irritation; drowsiness and narcosis; headache; vomiting; and liver and kidney damage. Related compounds cause severe lung injury if aspirated and mucous membrane injury.

Hazards Summary · 1 item

Corrosive to skin; [Quick CPC] Can cause narcosis and injury to the kidneys and liver; An irritant that may be corrosive to tissues and may cause severe lung injury if aspirated; [CAMEO] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Alfa Aesar MSDS] See 1-Chloro-2-propanol.

Reactive GroupAlcohols and Polyols

Safety & protection

Fire FightingFires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:

Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Toxicology

Adverse EffectsNeurotoxin - Acute solvent syndrome

Safety data

PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 3
tsca: TSCA listed
rtecs: UA7388000
ridadr: UN 2920 8/PG 2
hs_code: 29055998
risk_code: 10-34
Signal word: Warning
Symbol(GHS): GHS02,GHS07
hazard_code: C
safety_code: 26-36/37/39-45
hazard_class: 3.2
Storage Class: 3 - Flammable liquids
packing_group: III
Hazard statements: H226-H315-H319
Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
Hazard Classifications: Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2
Precautionary statements: P210-P233-P240-P241-P303+P361+P353-P305+P351+P338

Chemistry & industry

Uses & manufacturing

General Manufacturing Information2-Propanol, 1-bromo-: INACTIVE

Applications

UsesConformational isomerism of 1-bromo-2-propanol has been investigated by NMR spectroscopy.

General DescriptionColorless to dark brown liquid.

Upstream & downstream products

Upstream raw materials

4-METHYL-2-HEXANOL sec-BuMgBr, Fandachem

Downstream products

1-DIETHYLAMINO-2-PROPANOL 1-(2-benzylphenoxy)propan-2-ol

Suppliers56 total

湖北永阔科技有限公司027-59223108 15972152991 · [email protected]

湖北万得化工有限公司15377098680 15377098680 · [email protected]

合肥翰刚医药科技有限公司+8618062405514 · [email protected]

河南多贝化工有限公司0370-6999054 17550096163 · [email protected]

杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]

Additional notes

DefinitionChEBI: 1-bromo-2-propanol is a secondary alcohol that is propan-2-ol substituted by a bromo group at position 1. It has a role as a human metabolite. It is an organobromine compound and a secondary alcohol.