Acetonitrile → tert-Butyl (1-(2-hydroxypropyl)piperidin-4-yl)carbamate

HRID 123566

Reaction equation

HRID 123566 reaction equation
[Br:15][CH2:16][CH:17]([CH3:18])[OH:19].[Br:20][CH:21]([CH3:22])[CH2:23][OH:24].[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:32][C:33]#[N:34].[NH:1]1[CH2:2][CH2:3][CH:4]([NH:7][C:8]([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[CH2:5][CH2:6]1>>[N:1]1([CH2:16][CH:17]([CH3:18])[OH:19])[CH2:2][CH2:3][CH:4]([NH:7][C:8]([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 117132-Bromopropan-1-olHCID 297401-Bromo-2-propanolHCID 7238334-(N-Boc-amino)piperidine

Product 1

HCID 56973353tert-Butyl (1-(2-hydroxypropyl)piperidin-4-yl)carbamate

Sources & evidence

ORD record
ord-f4cdb0a5540a468bb598b89bb8795db0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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