HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Naphthalen-2-yl)hydrazine
AKOS AUF0417 · 2-NAPHTHYL HYDRAZINE · 2-HYDRAZINONAPHTHALENE · 2-NAPHTHALENYLHYDRAZINE · BETA-NAPHTHYL HYDRAZINE · phthalen-2-yl-hydrazine · NAPHTHALEN-2-YL-HYDRAZINE · hydrazine, 2-naphthalenyl-
Identifiers & Physical Properties
| CAS No. | 2243-57-4 |
|---|---|
| Molecular formula | C10H10N2 |
| Average molar mass | 158.2 g/mol |
| Monoisotopic mass | 158.08439833 g/mol |
| SMILES | NNc1ccc2ccccc2c1 |
| InChIKey | VNICRWVQYFRWDK-UHFFFAOYSA-N |
| PubChem CID | 407448 |
| ChEMBL | CHEMBL6172043 |
| EC No. | 822-033-7 |
| DTXSID | DTXSID101034443 |
Chemical & Physical Properties
| XLogP | 2.7 |
|---|---|
| Topological polar surface area | 38.1 |
| Hydrogen bond donors | 2 |
| Hydrogen bond acceptors | 2 |
| Rotatable bonds | 1 |
| Heavy atoms | 12 |
| Formal charge | 0 |
| Complexity | 147 |
| Boiling point | 362.9±11.0 °C(Predicted) |
| Density | 1+-.0.06 g/cm3(Predicted) |
| pKa (acidity coefficient) | 5.66±0.70(Predicted) |
| CAS DataBase Reference | 2243-57-4(CAS DataBase Reference) |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
| Hazard class | IRRITANT |
Safety & Regulations
| GHS classification | WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]H341 (100%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]P203, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (100%)Skin Irrit. 2 (100%)Skin Sens. 1 (100%)Eye Irrit. 2A (100%)STOT SE 3 (100%)Muta. 2 (100%)Carc. 2 (100%) |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard class | IRRITANT |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
Applications & Uses
Uses
2-Naphthylhydrazine-D3 is an intermediate used in the synthesis of Indocyanine Green-d12 (I697002), which is an isotopic analog of Indocyanine Green (I697000), a tricarbocyanine type of dye with infrared absorbing properties that can be used as a diagnostic aid (blood volume determination, cardiac output, hepatic function).