4-Morpholinopyridine

HCID 4145413

Notes Reactions

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Basic information

CAS: 2767-91-1
Standard SMILES: c1cc(N2CCOCC2)ccn1
InChIKey: QJWQYVJVCXMTJP-UHFFFAOYSA-N
Molecular formula: C9H12N2O
Average molar mass: 164.2 g/mol
Monoisotopic mass: 164.09496301

Names & identifiers

Preferred name: 4-Morpholinopyridine
IUPAC: 4-pyridin-4-ylmorpholine
English name: 4-Morpholinopyridine
Molecular formula: C9H12N2O
Molecular weight: 164.2

Names & synonyms

4-Morpholinopyridine2767-91-14-(4-Pyridyl)morpholineDTXSID20399887RefChem:525792DTXCID90350743627-998-64-(pyridin-4-yl)morpholineMorpholine, 4-(4-pyridinyl)-4-pyridin-4-ylmorpholineMFCD007040544-(4-Morpholinyl)pyridine

Show more names

SKL3334-MORPHOLINOPYRIDINE 97%4-(4-Pyridinyl)Morpholine4-(4-Pyridyl)morpholine>Morpholine, 4-(4-pyridinyl)-4-(4-Morpholinyl)pyridine, 97%

4-Morpholinopyridine, 97%SCHEMBL49166SCHEMBL1880062SCHEMBL4466700CHEMBL1643354AKOS005206806AS-59396SY037668

Database identifiers

CAS: 2767-91-1
PubChem CID: 4145413
DTXSID: DTXSID20399887
ChEMBL: CHEMBL1643354
EC Number: 627-998-6
Nikkaji: J482.061D

Properties

Computed structural properties

XLogP: 0.6
Topological polar surface area: 25.4 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 3
Rotatable bonds: 1
Heavy atoms: 12
Formal charge: 0
Complexity: 128

Physicochemical properties

Melting point: 102 · 102-108 °C (lit.)
Boiling point: 301.3 · 301.3±32.0 °C(Predicted)
Density: 1.124 · 1.124±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
pka: 7.97 · 7.97±0.26(Predicted)
form: Powder
color: Yellow to orange
InChI: InChI=1S/C9H12N2O/c1-3-10-4-2-9(1)11-5-7-12-8-6-11/h1-4H,5-8H2
InChIKey: QJWQYVJVCXMTJP-UHFFFAOYSA-N
SMILES: N1(C2C=CN=CC=2)CCOCC1
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 315 · H315-H319-H335

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 4 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Safety data

PPE: dust mask type N95 (US), Eyeshields, Gloves
wgk: 3
hs_code: 2934999090
risk_code: 36/37/38
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi
safety_code: 26-36
Storage Class: 11 - Combustible Solids
target organs: Respiratory system
Hazard statements: H315-H319-H335
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338

Chemistry & industry

Applications

Uses4-Morpholinopyridine may be used in the synthesis of 1-alkyl-4-morpholinopyridinium halides. It may also be used as a secondary enhancer to improve the chemiluminescence of horseradish peroxidase (HRP) catalyzed oxidation of luminol.

General Description4-Morpholinopyridine (MORP) can be synthesized by the reduction of its 1-oxide. It undergoes morpholine ring contraction on reacting with trimethylsilylmethyllithium (TMSCH2Li).

Upstream & downstream products

Upstream raw materials

Methyl vinyl sulfone

Suppliers99 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]

毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]

ShanghaiFineBiotechCoLtd+8618717800556 18717800556 · [email protected]

Related reactions

1 records

New reaction record

HRID 1391082As productuspto-grants-1979_02

Compound notes

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