Basic information
- CAS
19246-18-5- Standard SMILES
N[C@@H](CS)C(=O)NCC(=O)O- InChIKey
ZUKPVRWZDMRIEO-VKHMYHEASA-N- Molecular formula
- C5H10N2O3S
- Average molar mass
- 178.21 g/mol
- Monoisotopic mass
- 178.04121336
Names & identifiers
- Preferred name
- L-Cysteinylglycine
- IUPAC
- 2-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]acetic acid
- English name
- Cys-Gly
- Molecular formula
- C5H10N2O3S
- Molecular weight
- 178.21
Names & synonyms
Cysteinylglycine19246-18-5L-CysteinylglycineCys-GlyL-Cysteinyl-glycineN-L-cysteinylglycinecysteinyl-glycineGlycine, N-L-cysteinyl-QUINTESCINEDTXSID108648772-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]acetic acid384644SZ9T
Show more names
Gly-CysL-CYSTEINYL GLYCINECys-Gly-OHH-CYS-GLY-OHL-Cys-Gly-OHCYS-GLY USP/EP/BPN-Cysteinylglycineglycine,n-cysteinyl
2-[(2R)-2-amino-3-sulfanylpropanamido]acetic acidCHEBI:40472-((2R)-2-amino-3-sulfanylpropanamido)acetic acid2-(((2R)-2-amino-3-sulfanylpropanoyl)amino)acetic acid2-(((2R)-2-azaniumyl-3-sulfanylpropanoyl)amino)acetate2-[[(2R)-2-azaniumyl-3-sulfanylpropanoyl]amino]acetateRefChem:581400DTXCID901333734
Database identifiers
- CAS
19246-18-5- PubChem CID
- 439498
- DTXSID
DTXSID10864877- ChEMBL
CHEMBL371579- ChEBI
CHEBI:4047- UNII
- 384644SZ9T
- EC Number
- 633-715-7
- Nikkaji
- J36.789C
Properties
Computed structural properties
- XLogP
- -3.7
- Topological polar surface area
- 93.4 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 162
Experimental & physicochemical properties
Physical DescriptionSolid
Collision Cross Section131.77 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
Physicochemical properties
- Melting point
- 158 · 158 - 160oC
- Boiling point
- 459 · 459.0±45.0 °C(Predicted)
- Density
- 1.373 · 1.373±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- pka
- 3.02 · 3.02±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- Stability
- Air Sensitive
- InChI
- 1S/C5H10N2O3S/c6-3(2-11)5(10)7-1-4(8)9/h3,11H,1-2,6H2,(H,7,10)(H,8,9)
- InChIKey
- ZUKPVRWZDMRIEO-UHFFFAOYSA-N
- SMILES
- NC(CS)C(=O)NCC(O)=O
- FDA UNII
- 384644 SZ9T · 384644SZ9T
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 26 · NA.26
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H319
- Precautionary statements
- 301 · P301+P312+P330-P305+P351+P338
- PPE
- 95 · dust mask type N95 (US), Eyeshields, Gloves
- Hazard Codes
- Xn
- Risk Statements
- 22 · 22-36
- Safety Statements
- 26 · 26
- WGK Germany
- 3 · 3
- RTECS
- 9285800 · MB9285800
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 4 OralEye · Acute Tox. 4 OralEye Irrit. 2
Safety & regulation
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)；Eye Irrit. 2 (100%)
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- rtecs
- MB9285800
- risk_code
- 22-36
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- safety_code
- 26
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H319
- Hazard Classifications
- Acute Tox. 4 OralEye Irrit. 2
- Precautionary statements
- P301+P312+P330-P305+P351+P338
Chemistry & industry
Pharmacology
Tissue LocationsPlacenta
Cellular LocationsCytoplasm；Extracellular
Metabolite Pathways5-oxoprolinase deficiency；5-Oxoprolinuria；Gamma-glutamyl-transpeptidase deficiency；Gamma-Glutamyltransferase Deficiency；Glutathione metabolism；Glutathione Synthetase Deficiency
Applications
UsesCys-Gly has been used for derivatization by p-hydroxymercury benzoate (PHMB) for calibration of reversed phase chromatography coupled on-line and sequentially with a UVvisible diode array detector (RPLC-DAD).
General DescriptionCys-Gly, a dipeptide is a catabolic byproduct of glutathione.
Suppliers100 total
苏州道澜生物医药科技有限公司15952404857 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
河南赢创生物科技有限公司16650615803 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
南京昱盛康生物科技有限公司13327808530 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
郑州德元凯化工有限公司17837139533 · [email protected]
Syntechem Co.,Ltd[email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
上海晶抗生物工程有限公司021-54721350 13524668266 · [email protected]
中科华药(江苏)生物科技有限公司18020125070 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
希瓦生物科技（广州）有限公司13268215580 · [email protected]
上海柯维化学技术有限公司021-64609169 18901607656 · [email protected]
上海泰坦科技股份有限公司400-6009262 15618770481 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
佛山宝诺生物科技有限公司0757-85921206 18520245316 · [email protected]
Creative Peptides[email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
湖南汇百侍生物科技有限公司0731-85526065 13308475853 · [email protected]
上海源叶生物科技有限公司13636370518 · [email protected]
康明永瑞生物科技（苏州）有限公司17751201929 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
南京杜莱生物技术有限公司025-84699383-8003;025-846993838003-8003 18013301590 · [email protected]
上海倍卓生物科技有限公司021-61119791,13386096464 · [email protected]
上海毕得医药科技股份有限公司400-164-7117 18317119277 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
雷丁试剂0510-85629785 18013409632 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
江苏艾康生物医药研发有限公司025-66028182 17714375163 · [email protected]
陕西缔都医药化工有限公司029-81024372 17792795018 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
珠海安哲生物科技有限公司13169972583 · [email protected]
TargetMol中国（陶术生物）021-021-33632979 15002134094 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
北京诺其雅盛生物科技有限公司4000-819-385 010-62329685 13718666987
BOC Sciences16314854226; +8616314854226 · [email protected]
上海谱振生物科技有限公司4001650900 13817534909 · [email protected]
Additional notes
DefinitionChEBI: A dipeptide consisting of glycine having an L-cysteinyl attached to its alpha-amino group. It is an intermediate metabolite in glutathione metabolism.
Related reactions
2 records
Compound notes
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