Sulfo-SMCC sodium

HCID 4618794CAS 92921-24-9
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Basic information

Standard SMILES
O=C(ON1C(=O)CC(S(=O)(=O)[O-])C1=O)C1CCC(CN2C(=O)C=CC2=O)CC1.[Na+]
InChIKey
VUFNRPJNRFOTGK-UHFFFAOYSA-M
Molecular formula
C16H17N2NaO9S
Average molar mass
436.4 g/mol
Monoisotopic mass
436.0552454

Overview

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Names & identifiers

Preferred name
Sulfo-SMCC sodium
IUPAC
sodium 1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
English name
SULFO-SMCC
Molecular formula
C16H19N2NaO9S
Molecular weight
438.38

Names & synonyms

Sulfo-SMCC sodiumHH32D7TN36Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt3-Pyrrolidinesulfonic acid, 1-(((4-((2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl)cyclohexyl)carbonyl)oxy)-2,5-dioxo-, sodium saltCyclohexanecarboxylic acid, 4-((2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl)-, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester, sodium salt (1:1)RefChem:88956792921-24-9Sulfo-SMCCMFCD00054978Sulfo-SMCC (sodium)Sulfo-SMCC CrosslinkerSulfo-SMCC Sodium Salt
Show more names
4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-Cyclohexanecarboxylic acid 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester sodium salt (1:1)4-(N-MSlfo-SMCCCream IntermediateSMCC, WATER-SOLUBLESulpho SMCC sodium salt
sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-carbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonateC16H17N2NaO9SSulfo-N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate, Sodium SaltSulphosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium saltSulfo-N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate, Sodium Salt, 90%Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonateSodium 1-(4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyloxy)-2,5-dioxopyrrolidine-3-sulfonate92921-24-9 (sodium)

Database identifiers

CAS
92921-24-9
PubChem CID
4618794
DTXSID
DTXSID80404961
UNII
HH32D7TN36
Nikkaji
J1.801.515C、J934.770D

Properties

Computed structural properties

Topological polar surface area
167 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
9
Rotatable bonds
6
Heavy atoms
29

Physicochemical properties

Melting point
270 °C · >270°C (dec.)
storage temp.
-20 °C · Inert atmosphere,Store in freezer, under -20°C
solubility
2 O: · H2O: soluble2.5mg/mL
form
powder
color
white to light brown
Water Solubility
Soluble in water (2.5 mg/ml) and dimethyl formamide.

Safety & regulation

Safety data

wgk
3
hs_code
29251900
risk_code
36/37/38-20/21-61
Signal word
Warning
Symbol(GHS)
GHS07
hazard_code
Xi

Chemistry & industry

Applications · 3 items

DescriptionSulfo-SMCC is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

UsesA sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms

UsesA sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 11.6 Angstroms

Suppliers50 total

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]

Related reactions

3 records
New reaction record

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