Basic information
- Standard SMILES
Nc1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)n1- InChIKey
PCDQPRRSZKQHHS-UHFFFAOYSA-N- Molecular formula
- C9H16N3O14P3
- Average molar mass
- 483.16 g/mol
- Monoisotopic mass
- 482.98451208
Names & identifiers
- Preferred name
- Cytidine triphosphate disodium salt
- IUPAC
- [[5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
- English name
- Cytidine 5'-triphosphate disodium salt
- Molecular formula
- C9H17N3NaO14P3
- Molecular weight
- 507.15
Names & synonyms
Show more names
Database identifiers
- CAS
36051-68-0- PubChem CID
- 593
- DTXSID
DTXSID20861610
Properties
Computed structural properties
- XLogP
- -5.6
- Topological polar surface area
- 268 Ų
- Hydrogen bond donors
- 7
- Hydrogen bond acceptors
- 14
- Rotatable bonds
- 8
- Heavy atoms
- 29
- Formal charge
- 0
- Complexity
- 855
Physicochemical properties
- Flash point
- 113 °C · 113 °C
- storage temp.
- -20 °C · -20°C
- solubility
- 2 O: · H2O: 50 mg/mL, clear, colorless
- form
- Powder
- color
- White
- Water Solubility
- Soluble in water. Insoluble in ethanol, chloroform and ether.
- InChIKey
- LGADHEWLYMMGHW-RFFBCSJBNA-N
- SMILES
- O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.[NaH] |&1:1,2,3,19,r|
- CAS DataBase Reference
- 36051 · 36051-68-0(CAS DataBase Reference)
- FDA UNII
- 7 D7ZF20MNG · 7D7ZF20MNG
- UNSPSC Code
- 41106305 · 41106305
- NACRES
- 77 · NA.77
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- Safety Statements
- 24 · 24/25
- WGK Germany
- 3 · 3
- F
- 10 · 10-21
- HS Code
- 29349990 · 29349990
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety data
- F
- 10-21
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- hs_code
- 29349990
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 24/25
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
DescriptionCytidine 5'-triphosphate disodium salt is a nucleoside triphosphate with a pyrimidine ring, which is present in RNA. It is a nucleotide derivative and is involved in phospholipid anabolism in vivo. It can cross the blood-cerebrospinal fluid barrier. It is the intermediate product and energy source of cephalin synthesis and nucleic acid metabolism. It can also improve the stability and reconstruction ability of nerve cell membrane structure, support nerve cell survival, delay cell aging and death, and improve nerve cells. Injury resistance, promote neurite outgrowth.
UsesCytidine-5'-triphosphate disodium salt is a cation-permeable ligand gated ion channel (P2X purinergic receptor) agonist. It is also used as an organic intermediate, pharmaceutical intermediate, food additive and flavoring agent.
UsesCytidine 5'-triphosphate disodium salt is a pyrimidine nucleoside triphosphate salt that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.[Cayman Chemical]
General DescriptionCytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.
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