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Sodium sulfate decahydrate

HCID 62649
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Basic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
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Basic information

CAS
7727-73-3
Standard SMILES
O.O.O.O.O.O.O.O.O.O.O=S(=O)([O-])[O-].[Na+].[Na+]
InChIKey
RSIJVJUOQBWMIM-UHFFFAOYSA-L
Molecular formula
H20Na2O14S
Average molar mass
322.2 g/mol
Monoisotopic mass
322.03691488

Overview

Sodium sulfate decahydrate is a hydrate. It has a role as a cathartic. It contains a sodium sulfate.

Names & identifiers

Preferred name
Sodium sulfate decahydrate
IUPAC
disodium;sulfate;decahydrate
English name
SODIUM SULFATE DECAHYDRATE
Molecular formula
H20Na2O14S
Molecular weight
322.19

Names & synonyms

SODIUM SULFATE DECAHYDRATE7727-73-3Disodium sulfate decahydrateSodium sulfate [USP]Sodium sulfate (USP)DTXSID80228003RefChem:931933Sulfuric acid sodium salt (1:2), hydrate (1:10)DTXCID60150494SODIUM SULFATE, DECAHYDRATE616-445-4disodium;sulfate;decahydrate
Show more names
GLAUBER SALTSODIUM SULPHATE DECAHYDRATEGLAUBER'S SALTSodium sulfate hydratedSODIUM SULPHATE IOH2OsopdiumsulfatedecahydrateDecahydrate sodium sulfateSODIUM SULPHATE 10-HYDRATE
Guna-allergy-prevUNII-0YPR65R21JSodium sulfate (Na2SO4) decahydrateSodium sulfate decahydrate (Na2SO4.10H2O)Disodium sulfate decahydrate (Na2SO4.10H2O)MFCD00149189Sodium sulfafe decahydrateGlaubersalz

Database identifiers

CAS
7727-73-3
PubChem CID
62649

Properties

Computed structural properties

Topological polar surface area
98.6 Ų
Hydrogen bond donors
10
Hydrogen bond acceptors
14
Rotatable bonds
0
Heavy atoms
17
Formal charge
0
Complexity
62.2

Physicochemical properties

Melting point
32 · 32-38°C
Density
1.46 g/mL · 1.46 g/mL at 25 °C(lit.)
bulk density
700 kg/m3 · 700kg/m3
storage temp.
15 °C · Store at +15°C to +25°C.
solubility
2 O: · H2O: 1 M at 20 °C, clear, colorless
form
Solid
Specific Gravity
1.46 · 1.46
color
White
PH
5.2 · 5.2-8.0 (50g/l, H2O, 25℃)(anhydrous substance)
Water Solubility
Soluble in water and glycerin. Insoluble in ethanol and methanol.
λmax
260 nm · λ: 260 nm Amax: ≤0.025λ: 280 nm Amax: ≤0.021
Merck
14 · 14,8680
Stability
Stable. Incompatible with strong acids, aluminium, magnesium.
Cosmetics Ingredients Functions
VISCOSITY CONTROLLINGBULKING
InChI
1S/2Na.H2O4S.10H2O/c;;1-5(2,3)4;;;;;;;;;;/h;;(H2,1,2,3,4);10*1H2/q2*+1;;;;;;;;;;;/p-2

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 3 items

This chemical does not meet GHS hazard criteria for 100% (61 of 61) of all reports.

Not Classified

Aggregated GHS information provided per 61 reports by companies from 2 notifications to the ECHA C&L Inventory.

Hazard information

Regulatory Information · 2 items

Chemical: Sulfuric acid sodium salt (1:2), hydrate (1:10)

Sodium sulfate, decahydrate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Sulfuric acid, disodium salt, decahydrate: Human health tier I assessment
Hazard Classes and CategoriesNot Classified

Safety data

PPE
Eyeshields, Gloves, type N95 (US)
wgk
1
tsca
Yes
hs_code
28331900
Signal word
Warning
Symbol(GHS)
GHS07
safety_code
24/25
Storage Class
13 - Non Combustible Solids
Hazard statements
H302-H315-H319-H335
Precautionary statements
P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Chemistry & industry

Pharmacology

MeSH Pharmacological ClassificationAgents that are used to stimulate evacuation of the bowels.

Uses & manufacturing

Household ProductsInformation on 13 consumer products that contain Sodium sulfate decahydrate in the following categories is provided:
Applications · 5 items

OccurrenceSodium sulfate occurs in nature as the minerals mirabilite and thenardite. While thenardite is the anhydrous form of Na2SO4, mirabilite is a naturallyoccurring decahydrate, Na2SO4•10H2O. Sodium sulfate is one of the most important sodium salts. The decahydrate,commonly known as the Glauber’s salt, was first prepared by Johann Glauber in the seventeenth century as a by-product in making hydrochloric acid from sulfuric acid and sodium chloride.

UsesSodium sulfate decahydrate is used as a laboratory reagent to precipitate protein. It is largely used as filler in powdered home laundry detergents. It facilitates in leveling, reducing negative charges on fibers, thereby allows dye to penetrate evenly. It avoids the corrosion of stainless steel vessels used in dyeing. It is also used as a laxative and effectively replaces the drug paracetamol in the body.

UsesSodium sulfate decahydrate may be used to deepen the color while dyeing cotton fabrics.6

UsesSodium sulfate decahydrate is used in manufacturing paper pulp by the Kraft Process. Other uses are in manufacturing glass and ultramarine; in dyeing and printing textiles; as a filler in synthetic detergents; and for standardizing dyes. A major use of anhydrous sodium sulfate is as an agent to remove water from organic solvents and their extracts for organic synthesis and instrumental analysis. Sodium sulfate decahydrate is a common laboratory reagent. Also, it is used to prepare other sodium salts.

General DescriptionSodium sulfate decahydrate (Glauber′s salt, mirabilite, Na2SO4·10H2O) is the decahydrate salt of sodium sulfate. Its crystal structure has been investigated by single-crystal neutron diffraction studies. Its crystallization enthalpy has been evaluated. It can be synthesized by reacting MnSO4, thiophene-2,5-dicarboxylic acid and sodium glutamate.

Related reactions

508 records
New reaction record
HRID 6956 reaction equation
HRID 6956As reactantuspto-grants-2006_08
HRID 10338 reaction equation
HRID 10338As reactantuspto-grants-2006_08
HRID 14401 reaction equation
HRID 14401As reactantuspto-grants-2010_06
HRID 15046 reaction equation
HRID 15046As reactantuspto-grants-2010_06
HRID 15627 reaction equation
HRID 15627As reactantuspto-grants-2010_06
HRID 23403 reaction equation
HRID 23403As reactantuspto-grants-2005_02
HRID 30622 reaction equation
HRID 30622As reactantuspto-grants-2008_09
HRID 36013 reaction equation
HRID 36013As reactantuspto-grants-1995_05
Page 1 of 64

Compound notes

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DTXSID
DTXSID80228003
ChEMBL
CHEMBL3989856
ChEBI
CHEBI:32586
UNII
0YPR65R21J
EC Number
616-445-4
InChIKey
RSIJVJUOQBWMIM-UHFFFAOYSA-L
SMILES
O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O
LogP
-1.031 · -1.031 (est)
CAS DataBase Reference
7727 · 7727-73-3(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)
SODIUM SULFATE
FDA 21 CFR
173.31 · 173.310; 177.1200; 186.1797
FDA UNII
0 YPR65R21J · 0YPR65R21J
EPA Substance Registry System
Disodium sulfate decahydrate (7727-73-3)
UNSPSC Code
12352302 · 12352302
NACRES
24 · NB.24
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
302 · H302-H315-H319-H335
Precautionary statements
261 · P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
PPE
95 · Eyeshields, Gloves, type N95 (US)
Safety Statements
24 · 24/25
WGK Germany
1 · 1
TSCA
Yes
HS Code
28331900 · 28331900
Storage Class
13 · 13 - Non Combustible Solids

Upstream & downstream products

Upstream raw materials

Sodium sulfateSodium chlorideBITTERNPotassium chloride

Downstream products

Tocopheryl acetatebloediteStrontium carbonate2-Ethylpiperazine2-Amino-4,6-difluorobenzoic acidTanning agent,chromicCalcium phosphateSodium sulfideSodium sulfate2,6-Difluoro-4-hydroxybenzonitrileSodium bisulfate monohydrateSodium silicateChromium sulfate,basic,solidSilk softener LSodium carbonateBarium sulfate

Additional notes

DefinitionChEBI: Sodium sulfate decahydrate is a hydrate. It has a role as a cathartic. It contains a sodium sulfate.