Basic information
- CAS
15491-23-3- Standard SMILES
O.O.O.O.O.O.O.O=S(=O)([O-])[O-].[Fe+2]- InChIKey
SURQXAFEQWPFPV-UHFFFAOYSA-L- Molecular formula
- FeH14O11S
- Average molar mass
- 278.02 g/mol
- Monoisotopic mass
- 277.96061977
Overview
Iron(2+) sulfate heptahydrate is a hydrate that is the heptahydrate form of iron(2+) sulfate. It is used as a source of iron in the treatment of iron-deficiency anaemia (generally in liquid-dosage treatments; for solid-dosage treatments, the monohydrate is normally used). It has a role as a nutraceutical, a reducing agent and an anti-anaemic agent. It is an iron molecular entity and a hydrate. It contains an iron(2+) sulfate (anhydrous).
Names & identifiers
- Preferred name
- Ferrous sulfate heptahydrate
- IUPAC
- iron(2+);sulfate;heptahydrate
- English name
- Ferrous sulfate heptahydrate
- Molecular formula
- FeH14O11S
- Molecular weight
- 278.01
Names & synonyms
7782-63-0Iron(II) sulfate heptahydrateFERROUS SULFATE HEPTAHYDRATEIron(2+) sulfate heptahydrateIron sulfate heptahydrateMelanterite mineralFesotymeIrosulSiderotil mineralTauriscite mineralSzomolnikite mineralFerrous sulfate, heptahydrate
Show more names
FERROINsulfate heptahydrateFERROIN INDICATOR SOLUTIONIron(Ⅱ) sulfate heptahydrateFERROIN INDICATORFerrous sulfate heptferrous sulfate granularFerrousSulphateMonohydrateIron(II)sulphateheptahydrate,98%
Iron(II) sulfate (1:1), heptahydrateTetucur-SDTXSID9040344CHEBI:75836RefChem:921576DTXCID7020344616-510-7Melanterite
Database identifiers
- CAS
15491-23-3、7782-63-0- PubChem CID
- 62662
- DTXSID
DTXSID9040344- ChEBI
CHEBI:75836- UNII
- 39R4TAN1VT
- EC Number
- 616-510-7
Properties
Computed structural properties
- Topological polar surface area
- 95.6 Ų
- Hydrogen bond donors
- 7
- Hydrogen bond acceptors
- 11
- Rotatable bonds
- 0
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 62.2
Experimental & physicochemical properties
Chemical ClassesMetals -> Metals, Inorganic Compounds
Density1.895 @25 °C
Physical Description
CBI
Blue-green odorless solid; Efflorescent in dry air; Soluble in water; [Merck Index] Green crystalline solid; [Alfa Aesar MSDS]
Physicochemical properties
- Melting point
- 64 °C · 64 °C
- Density
- 1.898 g/mL · 1.898 g/mL at 25 °C (lit.)
- bulk density
- 600 kg/m3 · 600kg/m3
- vapor pressure
- 14.6 mm · 14.6 mm Hg ( 25 °C)
- storage temp.
- 15 °C · Store at +15°C to +25°C.
- solubility
- 25.6 g/100 · 25.6 g/100 mL (20°C)
- form
- Solution
- Specific Gravity
- 1.898 · 1.898
- color
- Slightly greenish to blue
- Odor
- pale bluish-grn. cryst. or gran., odorless
- PH
- 3 · 3.0-4.0 (25℃, 50mg/mL in H2O)
- Water Solubility
- 25.6 g/100 · 25.6 g/100 mL (20 ºC)
- Sensitive
- Air Sensitive & Hygroscopic
- Merck
- 14 · 14,4057
- Exposure limits
- 1 mg/m3NIOSH: · ACGIH: TWA 1 mg/m3NIOSH: TWA 1 mg/m3
- Stability
- Stable. Substances to be avoided include strong oxidizing agents. Air and moisture sensitive.
- InChI
- 1S/Fe.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2
- InChIKey
- SURQXAFEQWPFPV-UHFFFAOYSA-L
- SMILES
- [Fe+2].[S](=O)(=O)([O-])[O-].O.O.O.O.O.O.O
- LogP
- -1.031 · -1.031 (est)
- CAS DataBase Reference
- 7782 · 7782-63-0(CAS DataBase Reference)
- Substances Added to Food (formerly EAFUS)
- FERROUS SULFATE
- FDA UNII
- 39 R4TAN1VT · 39R4TAN1VT
- EPA Substance Registry System
- Ferrous sulfate heptahydrate (7782-63-0)
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 71 · NA.71
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319
- Precautionary statements
- 264 · P264-P270-P280-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22 · 22-36/38
- Safety Statements
- 36 · 36/37/39-46
- RIDADR
- 3077 · UN3077
- WGK Germany
- 1 · 1
- RTECS
- 8510000 · NO8510000
- F
- 10 · 10-23
- TSCA
- Yes
- HazardClass
- 9 · 9
- HS Code
- 28332950 · 28332950
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 4 OralEye · Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2
- Toxicity
- 50 in · LD50 in mice: 65 mg/kg i.v.; 1.52 g/kg orally (Hoppe)
- Limited Quantities
- 5 L · 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Safety & regulation
GHS classification
GHS Classification
Warning
H302: Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)
This chemical does not meet GHS hazard criteria for < 0.1% (2 of 2619) of reports.
Warning
H302 (> 99.9%): Harmful if swallowed [Warning Acute toxicity, oral]
Hazard information
Regulatory Information
Chemical: Sulfuric acid, iron(2+) salt (1:1), heptahydrate
Regulation (EC) No 1831/2003 (amended)
Sulfuric acid, iron(2+) salt (1:1), heptahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid, iron(2+) salt (1:1), heptahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Ferrous sulphate, heptahydrate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Sulfuric acid, iron(2+) salt (1:1), heptahydrate: Human health tier I assessment
Hazards Summary
A skin, eye, and mucous membrane irritant; May cause gastrointestinal disturbances, shock, cyanosis, coma, and liver damage; [Merck Index] A skin and strong eye irritant; Harmful by ingestion; [Alfa Aesar MSDS] See Ferrous sulfate. See Iron salts, soluble.
Hazard Classes and Categories
Acute Tox. 4 (> 99.9%)
Acute toxicity - category 4
Acute toxicity (Oral) - Category 4
Acute Tox. 4 *
Safety & protection
Threshold Limit Values (TLV)1.0 [mg/m3], as Fe (soluble iron salts)
Protective Action Criteria (PAC)
2.5 [mg/m3]
27 [mg/m3]
160 [mg/m3]
Toxicology
Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
Safety data
- F
- 10-23
- wgk
- 1
- tsca
- Yes
- rtecs
- NO8510000
- ridadr
- UN3077
- hs_code
- 28332950
- Toxicity
- LD50 in mice: 65 mg/kg i.v.; 1.52 g/kg orally (Hoppe)
- risk_code
- 22-36/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- safety_code
- 36/37/39-46
- hazard_class
- 9
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319
- Limited Quantities
- 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
- Hazard Classifications
- Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2
- Precautionary statements
- P264-P270-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Uses & manufacturing
Uses
Used in iron electroplating baths, fertilizers, pesticides, radiation dosimeters, writing ink, process engraving, lithography, dyeing leather, etching aluminum, water treatment, brown ring test for nitrates, and food and feed supplements; Also used as a reducing agent, wood preservative, weed killer, polymerization catalyst, plant food, and hematinic; [Merck Index] Formerly registered in the US as a moss killer/fertilizer for lawns; [NPIRS] Used as a nutritional supplement, processing aid, and stabilizer or thickener for foods; [FDA]
Aluminum Producing [Category: Industry]
Lithography printing [Category: Hobbies]
U.S. Production2023: 75,000 - <500,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesSoil amendments (fertilizers)
Household ProductsInformation on 27 consumer products that contain Ferrous sulfate heptahydrate in the following categories is provided:
General Manufacturing InformationPesticide, Fertilizer, and Other Agricultural Chemical Manufacturing
Applications
Description§184.1315(a) Ferrous sulfate heptahydrate (iron (II) sulfate heptahydrate, FeS04-7H2O) is prepared by the action of sulfuric acid on iron. It occurs as pale, blueish-green crystals or granules. Progressive heating of ferrous sulfate heptahydrate produces ferrous sulfate (dried). Ferrous sulfate (dried) consists primarily of ferrous sulfate monohydrate (CAS No. 17375-41-6) with varying amounts of ferrous sulfate tetrahydrate (CAS No. 20908-72-9) and occurs as a grayish-white to buff-colored powder.
UsesUsed in quantitative analysis of nitrates .
UsesIn manufacture of Fe, Fe Compounds, other sulfates; in Fe electroplating baths; in fertilizer; as food and feed supplement; in radiation dosimeters; as reducing agent in chemical processes; as wood preservative; as weed-killer; in prevention of chlorosis in plants; in other pesticides; in writing ink; in process engraving and lithography; as dye for leather; in etching aluminum; in water treatment; in qualitative analysis ("brown ring" test for nitrates); as polymerization catalyst.
UsesIron(II) sulfate heptahydrate is used as a precursor to prepare other iron compounds such as a lawn conditioner and a mordant for wool dyeing. It is actively used in the manufacture of ink including iron gall ink. As a reducing agent, it participates in the reduction of chromate in cement. It is also used in industrial water treatment plants to remove phosphate. It is also used in the gold refining process to precipitate metallic gold. Woodworkers use aqueous solutions of ferrous sulfate to color maple wood a silvery hue. It finds application in the treatment of iron chlorosis, which arises due to deficiency of iron in horticulture.
General DescriptionA greenish or yellow-brown crystalline solid. Density 15.0 lb /gal. Melts at 64°C and loses the seven waters of hydration at 90°C. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Used for water or sewage treatment, as a fertilizer ingredient.
Preparation methods
PreparationBy-product Method: byproduct of titanium dioxide production: Titanite is decomposed with sulfuric acid to obtain titanium dioxide, ferrous sulfate(II) and ferric sulfate (III). Iron (III) compounds are reduced to obtain iron (II) compounds. The mixture is then cooled and crystallized to form ferrous sulfate. 5H2SO4+2FeTiO3→2FeSO4+TiOS04+Ti(SO4)2+5H2O Sulfuric acid method Scrap iron is dissolved with a mixture of diluted sulfuric acid solution and mother solution. The reaction temperature should be below 80°C, otherwise, it results in the sedimentation of ferrous sulfate monohydrate. Clarification is applied to remove impurities from the slightly acidic ferrous sulfate solution. Cooling and centrifugation are carried out obtain light-green ferrous sulfate. Fe+H2SO4→FeSO4+H2↑
Upstream & downstream products
Upstream raw materials
Downstream products
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Additional notes
DefinitionChEBI: A hydrate that is the heptahydrate form of iron(2+) sulfate. It is used as a source of iron in the treatment of iron-deficiency anaemia (generally in liquid-dosage treatments; for solid-dosage treatments, the monohydrate is normally used).
Related reactions
91 records
Compound notes
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