Basic information
- CAS
86087-24-3- Standard SMILES
O[C@@H]1CCOC1- InChIKey
XDPCNPCKDGQBAN-SCSAIBSYSA-N- Molecular formula
- C4H8O2
- Average molar mass
- 88.11 g/mol
Names & identifiers
- Preferred name
- (-)-3-Hydroxytetrahydrofuran
- IUPAC
- (3R)-oxolan-3-ol
- English name
- (R)-(-)-3-Hydroxytetrahydrofuran
- Molecular formula
- C4H8O2
- Molecular weight
- 88.11
Names & synonyms
(-)-3-HydroxytetrahydrofuranRefChem:39092886087-24-3(R)-(-)-3-Hydroxytetrahydrofuran(R)-TETRAHYDROFURAN-3-OL(3R)-oxolan-3-ol(R)-3-HYDROXYTETRAHYDROFURAN(R)-(-)-tetrahydrofuran-3-ol(3R)-Tetrahydrofuran-3-olMFCD000671013-Furanol, tetrahydro-, (3R)-(R)-Tetrahydro-furan-3-ol
Show more names
Empagliflozin Impurity 67(3R)-Tetrahydrofuran-3α-olEmpagliflozin Impurity 1493-FURANOL, TETRAHYDRO-, (R)(R)-(-)-TETRAHYDRO-3-FURANOL3-Furanol, tetrahydro-,(3R)-
84976-47-6(3R)-tetrahydro-3-furanol3-Hydroxytetrahydrofuran, (R)-3-Furanol, tetrahydro-, (R)-(R)-(-)-3-Hydroxytetrahydrofuran, 98%CS-0045411(R)-(+)-3-HydroxytetrahydrofuranAM20110237
Database identifiers
- CAS
86087-24-3- PubChem CID
- 641512
- UNII
- AUS5N27VPH
- EC Number
- 617-796-6
- Nikkaji
- J146.587B
Properties
Computed structural properties
- XLogP
- -0.4
- Topological polar surface area
- 29.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 6
- Formal charge
- 0
- Complexity
- 44.8
Experimental & physicochemical properties
SpringerMaterials PropertiesSchoenflies notation
Physicochemical properties
- alpha
- -18.5 · -18.5 º (c=2 MeOH)
- Boiling point
- 181 °C · 181 °C (lit.)
- Density
- 1.097 g/mL · 1.097 g/mL at 25 °C (lit.)
- refractive index
- 20 · n20/D 1.45(lit.)
- Flash point
- 180 °F · 180 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform, Methanol (Slightly)
- form
- Liquid
- pka
- 14.49 · 14.49±0.20(Predicted)
- color
- Clear colorless
- Specific Gravity
- 1.097 · 1.097
- optical activity
- 20 · [α]20/D 18°, c = 2.4 in methanol
- InChI
Safety & regulation
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 42 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- PPE
- Eyeshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- ridadr
- NA 1993 / PGIII
- hs_code
- 29321900
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- hazard_class
- CBL
- Storage Class
- 10 - Combustible liquids
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335
- Excepted Quantities
- Non-Hazardous
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
Chemistry & industry
Applications
Uses(R)-(-)-3-Hydroxytetrahydrofuran is used as a chemical reactant in the synthesis of pharmaceutical agents. Empagliflozin is synthesized using this reactant
Uses(R)-(-)-3-Hydroxytetrahydrofuran may be used as building block in the synthesis of potent HIV protease inhibitors.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
Related reactions
59 records
Compound notes
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