Basic information
- Standard SMILES
C=C(C)C(N)=O- InChIKey
FQPSGWSUVKBHSU-UHFFFAOYSA-N- Molecular formula
- C4H7NO
- Average molar mass
- 85.1 g/mol
- Monoisotopic mass
- 85.05276384
Overview
Methacrylamide is a primary carboxamide and a member of acrylamides.
Names & identifiers
- Preferred name
- Methacrylamide
- IUPAC
- 2-methylprop-2-enamide
- English name
- Methacrylamide
- Molecular formula
- C4H7NO
- Molecular weight
- 85.1
Names & synonyms
METHACRYLAMIDE79-39-02-Methylacrylamide2-methylprop-2-enamideMethacrylic amideMethacrylic acid amide2-Methylpropenamide2-Propenamide, 2-methyl-Methylacrylic amideMhoromer BM801alpha-Methyl acrylic amideAmid kyseliny methakrylove
Show more names
Methylacrylamide2-methyl-2-Propenamideusafrh-1USAF rh-1mhoromerbm801
DTXSID8029600CHEBI:51759K67NG89J77NSC-23772DTXCID109600RefChem:156839201-202-3Methacryamide
Database identifiers
- CAS
79-39-0- PubChem CID
- 6595
- DTXSID
DTXSID8029600- ChEMBL
CHEMBL158237- ChEBI
CHEBI:51759- UNII
- K67NG89J77
- EC Number
- 201-202-3
- Nikkaji
- J38.885H
Properties
Computed structural properties
- XLogP
- 0.1
- Topological polar surface area
- 43.1 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 1
- Heavy atoms
- 6
- Formal charge
- 0
- Complexity
- 85.5
Experimental & physicochemical properties
Chemical ClassesIndustrial compound
PolymersPlastics & Rubber -> Other Monomers
SpringerMaterials PropertiesBoiling point
Boiling Point215 °C @760 [mm Hg]
Vapor Pressure0.1 [mmHg]
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical DescriptionWhite crystalline solid; [Alfa Aesar MSDS]
Physicochemical properties
- Melting point
- 106 · 106-110 °C (lit.)
- Boiling point
- 215 °C · 215 °C
- Density
- 1 · 1,115 g/cm3
- bulk density
- 550 kg/m3 · 550kg/m3
- vapor pressure
- 0.0015 hPa · 0.0015 hPa (20 °C)
- refractive index
- 1.3992 · 1.3992 (estimate)
- Flash point
- 215 °C · 215°C
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- 202 g/l · 202g/l
- form
- Crystals
- pka
- 15.46 · 15.46±0.50(Predicted)
- color
- White to very slightly yellow
- PH
- 7.1 · 7.1 (100g/l, H2O, 20℃)
- explosive limit
- 2 · 2-15%(V)
- Water Solubility
- 202 g/L · 202 g/L (20 ºC)
- BRN
- 605397 · 605397
- Henry's Law Constant
- 8.8 · 8.8×103 mol/(m3Pa) at 25℃, Ebert et al. (2023)
- InChI
- 1S/C4H7NO/c1-3(2)4(5)6/h1H2,2H3,(H2,5,6)
- InChIKey
- FQPSGWSUVKBHSU-UHFFFAOYSA-N
- SMILES
- CC(=C)C(N)=O
- CAS DataBase Reference
- 79 · 79-39-0(CAS DataBase Reference)
- Indirect Additives used in Food Contact Substances
- METHACRYLAMIDE
- FDA 21 CFR
- 177.101 · 177.1010; 177.1630
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 67 NG89J77 · K67NG89J77
- NIST Chemistry Reference
- Methacrylamide(79-39-0)
- EPA Substance Registry System
- Methacrylamide (79-39-0)
- UNSPSC Code
- 12352111 · 12352111
- NACRES
- 23 · NA.23
- Symbol(GHS)
- 7 · GHS07,GHS08
- Signal word
- Warning
- Hazard statements
- 302 · H302-H319-H335-H371-H373
- Precautionary statements
- 260 · P260-P264-P270-P301+P312-P305+P351+P338-P308+P311
- target organs
- Respiratory system
- Hazard Codes
- Xn
- Risk Statements
- 22 · 22-36/37/38
- Safety Statements
- 26 · 26-36/37
- RIDADR
- 3263 · 3263
- WGK Germany
- 1 · 1
- RTECS
- 6475000 · UC6475000
- Autoignition Temperature
- 510 °C · 510 °C
- TSCA
- TSCA listed
- HS Code
- 2924 · 2924 19 00
- HazardClass
- 6.1 · 6.1(b)
- PackingGroup
- III
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 4 OralEye · Acute Tox. 4 OralEye Irrit. 2STOT RE 2STOT SE 2STOT SE 3
- Toxicity
- 50 orally · LD50 orally in Rabbit: 1815 mg/kg LD50 dermal Rat > 5000 mg/kg
- REACH Registrations
- Active
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 0.9% (7 of 803) of reports.
Warning
H302 (99.1%): Harmful if swallowed [Warning Acute toxicity, oral]
P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P304+P340, P305+P351+P338, P308+P316, P319, P330, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 803 reports by companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
Hazard information
Regulatory Information
Chemical: 2-Propenamide, 2-methyl-
Status: Active Update: 14-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15801
Methacrylamide: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationEvaluation - 2-Propenamide, 2-methyl- (methacrylamide)
Hazards Summary
An eye irritant in rabbits; No to mild skin sensitization reactions seen in guinea pigs; Neurotoxicity observed in repeated-dose animal studies; [IUCLID] Marked developmental toxicity observed in mice at doses only slightly maternally toxic; [NTP] An irritant; Moderately toxic by ingestion and inhalation (degenerative changes of the liver, kidney, and brain); Reproductive effects observed in experimental animals; [Alfa Aesar MSDS] See Acrylamide.
Hazard Classes and Categories
Acute Tox. 4 (99.1%)
Acute toxicity (Oral) - Category 4
Safety & protection
Protective Action Criteria (PAC)
3.0 [mg/m3]
15 [mg/m3]
91 [mg/m3]
Toxicology
Adverse EffectsNeurotoxin - Other CNS neurotoxin
Safety data
- wgk
- 1
- tsca
- TSCA listed
- rtecs
- UC6475000
- ridadr
- 3263
- hs_code
- 2924 19 00
- Toxicity
- LD50 orally in Rabbit: 1815 mg/kg LD50 dermal Rat > 5000 mg/kg
- risk_code
- 22-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07,GHS08
- hazard_code
- Xn
- safety_code
- 26-36/37
- hazard_class
- 6.1(b)
- Storage Class
- 11 - Combustible Solids
- packing_group
- III
- target organs
- Respiratory system
- Hazard statements
- H302-H319-H335-H371-H373
- REACH Registrations
- Active
- Hazard Classifications
- Acute Tox. 4 OralEye Irrit. 2STOT RE 2STOT SE 2STOT SE 3
- Autoignition Temperature
- 510 °C
- Precautionary statements
- P260-P264-P270-P301+P312-P305+P351+P338-P308+P311
Chemistry & industry
Uses & manufacturing
Uses
A congener of acrylamide; [NTP] Used in the chemical, leather processing, paper-pulp-board, polymers, textile processing, and paints-lacquers-varnishes industries; Used as an adhesive, binding agent, corrosion inhibitor, and intermediate; [IUCLID]
Pulp and Paper Processing [Category: Industry]
General Manufacturing Information2-Propenamide, 2-methyl-: ACTIVE
Applications
UsesA monomer for acrylic resins.
UsesMethacrylamide is a reagent used in the production of polymers and copolymers. It is also used as a raw material in the production of chemicals for industrial and professional use such as textiles, leather, fur, bulk, large scale chemicals (including petroleum products), fine chemicals, formulation [mixing] of preparations and/or re-packaging (excluding alloys), building and construction work, electricity, steam, gas, water supply and sewage treatment.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers50 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
北京安司莫森技术有限公司010-82954736 13391601435 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海诗丹德标准技术服务有限公司021-021-57127007-6622-6622 17621252073 · [email protected]
济南世纪通达化工有限公司15605418165
湖北成海化工有限公司027-59220433 18327245847 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
玛雅试剂+86 (573) 82222445 (0)18006601000 452520369 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
常州琬瑶生物科技有限公司0519-89185693 15312551983 · [email protected]
艾科试剂4008-755-333 18080918076 · [email protected]
上海思域化工科技有限公司86-21-34053660 · [email protected]
赛默飞世尔科技（中国）有限公司800-810-5118 · [email protected]
北京伊诺凯科技有限公司400-810-7969 010-59572699 · [email protected]
上海健超生物科技有限公司150-2103-5486 18017383231 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
上海贤鼎生物科技有限公司4009209199 · [email protected]
越林试剂021-62960152 · [email protected]
上海将来实业股份有限公司400-0066400 13621662912 · [email protected]
上海将来实业股份有限公司021-61552785 · [email protected]
安徽科迪达化工有限公司0554-2106669 · [email protected]
成都零六生物科技有限公司400-1166-196 13458535857 · [email protected]
上海馨远医药科技有限公司021-24206007 13764915196 · [email protected]
杭州宇昊化工科技有限公司0571-82693216 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
上海嵩爰化工科技有限公司010-1234567 18521000990 · [email protected]
江苏艾康生物医药研发有限公司025-66028182 17714375163 · [email protected]
上海孚一生物科技有限公司+86 (21) 61124340
湖北巨胜科技有限公司027-59599241 18871490274 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
武汉天植生物技术有限公司18607101326 15172504745 · [email protected]
成都瑞欧克科技有限公司028-64353063 · [email protected]
Alfa Chemistry+1-5166625404 · [email protected]
成都润泽本土化工有限公司028-88469284 18000562381 · [email protected]
上海思言生物科技有限公司021-50908862，442785678，326799392 18721037013 · [email protected]
北京华威锐科化工科技有限公司89508211 18501085097 · [email protected]
Additional notes
DefinitionChEBI: Methacrylamide is a member of acrylamides and a primary carboxamide.
Related reactions
58 records
Linked notes
Loading…