Acetate → 3-[3-[5-Amino-3-(2-fluorophenyl)pyrazol-1-yl]phenyl]-2-methylprop-2-enamide

HRID 196719

Reaction equation

HRID 196719 reaction equation
[CH3:21][C:22](=[CH2:23])[C:24]([NH2:25])=[O:26].[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[F:1][c:2]1[c:3](-[c:8]2[n:9][n:10](-[c:14]3[cH:15][c:16]([I:20])[cH:17][cH:18][cH:19]3)[c:11]([NH2:13])[cH:12]2)[cH:4][cH:5][cH:6][cH:7]1.[O-:60][C:61]([CH3:62])=[O:63].[O-:64][C:65]([CH3:66])=[O:67].[O:53]=[CH:54][N:55]([CH3:56])[CH3:57].[OH2:58].[Pd+2:59].[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[F:1][c:2]1[c:3](-[c:8]2[n:9][n:10](-[c:14]3[cH:15][c:16]([CH:21]=[C:22]([CH3:23])[C:24]([NH2:25])=[O:26])[cH:17][cH:18][cH:19]3)[c:11]([NH2:13])[cH:12]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 962WaterHCID 6228DimethylformamideHCID 6595MethacrylamideHCID 8471TriethylamineHCID 11776TriphenylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 67272077HCID 67272077, compound

Product 1

HCID 672706533-[3-[5-Amino-3-(2-fluorophenyl)pyrazol-1-yl]phenyl]-2-methylprop-2-enamide

Sources & evidence

ORD record
ord-513284ca83ba49689dbff239d2a2067e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…