Mafenide Hydrochloride

HCID 67313CAS 138-37-4
Substructure searchFind similar structures

Basic information

Standard SMILES
Cl.NCc1ccc(S(N)(=O)=O)cc1
InChIKey
SIACJRVYIPXFKS-UHFFFAOYSA-N
Molecular formula
C7H11ClN2O2S
Average molar mass
222.69 g/mol
Monoisotopic mass
222.02297627

Overview

See also: Mafenide (has active moiety).

Names & identifiers

Preferred name
Mafenide Hydrochloride
IUPAC
4-(aminomethyl)benzenesulfonamide;hydrochloride
English name
Mafenide hydrochloride
Molecular formula
C7H11ClN2O2S
Molecular weight
222.69

Names & synonyms

Mafenide hydrochloride138-37-44-Aminomethylbenzenesulfonamide hydrochloride4-(Aminomethyl)benzenesulfonamide hydrochlorideHomosulfamine hydrochlorideMafenide HClMorfanilMasudinMesudin hydrochlorideAmbamide hydrochloride4-Homosulfanilamide hydrochlorideEmilene hydrochloride
Show more names
MAFENIDEMARFANILMAFENIDEHCLLABOTEST-BB LT00454465LABOTEST-BB LTBB000725MARFANIL HYDROCHLORIDEsulfamylonhydrochloride
Sulfamylon hydrochlorideSulfbenzamine hydrochlorideMesudrin hydrochlorideNeofamid hydrochlorideMaphenide hydrochlorideHomosulfanilamide hydrochlorideBenzenesulfonamide, 4-(aminomethyl)-, monohydrochlorideDTXSID6045296

Database identifiers

CAS
138-37-4、49783-80-4
PubChem CID
67313
DTXSID
DTXSID6045296
ChEMBL
CHEMBL1593568
UNII
3J751V0284
EC Number
205-325-3

Properties

Computed structural properties

Topological polar surface area
94.6 Ų
Hydrogen bond donors
3
Hydrogen bond acceptors
4
Rotatable bonds
2
Heavy atoms
13

Experimental & physicochemical properties

DrugsPharmaceuticals -> Antibiotics

Physicochemical properties

Melting point
261 · 261-263 °C(lit.)
storage temp.
Inert atmosphere,Room Temperature
solubility
DMSO (Slightly), Methanol (Slightly)
form
Solid
color
White
Merck
13 · 13,5671

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.

Hazard information

Hazard Classes and CategoriesSkin Sens. 1 (100%)

Safety data

PPE
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
wgk
2
rtecs
XT5425000
hs_code
29350090
Toxicity
LD50 in rats, mice (mg/kg): 1170, 900 i.v. (Skulan, Hoppe)
risk_code
42/43

Chemistry & industry

Applications

UsesAntibacterial;Inhibitor of folic acid biosynthesis

Upstream & downstream products

Suppliers50 total

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Related reactions

24 records
New reaction record

Linked notes

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