CAS 598-42-5 2-Hydroxyacetamide (HCID 69021)

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Basic information

CAS: 598-42-5
Standard SMILES: NC(=O)CO
InChIKey: TZGPACAKMCUCKX-UHFFFAOYSA-N
Molecular formula: C2H5NO2
Average molar mass: 75.07 g/mol
Monoisotopic mass: 75.0320284

Overview

2-hydroxyacetamide is a member of acetamides.

Names & identifiers

Preferred name: 2-Hydroxyacetamide
IUPAC: 2-hydroxyacetamide
English name: 2-HYDROXYACETAMIDE
Molecular formula: C2H5NO2
Molecular weight: 75.07

Names & synonyms

2-hydroxyacetamideGlycolamide598-42-5GlycollamideAcetamide, 2-hydroxy-2-Hydroxyacetimidic acid18EAK3UR7CDTXSID70208531NSC-97323CHEBI:30321RefChem:143914DTXCID20131022

Show more names

A-HYDROXYACETAMIDENSC 97323GlycolaMide 98%TIMTEC-BB SBB010080Dexrazoxane Impurity 15

814-440-3MFCD00047895Glycolic amide2-hydroxy-acetamidealpha-HydroxyacetamideAcetamide, 2-hydroxy-(9CI)Glycolic acid amideGlycolamide, 98%

Database identifiers

CAS: 598-42-5
PubChem CID: 69021
DTXSID: DTXSID70208531
ChEBI: CHEBI:30321
UNII: 18EAK3UR7C
EC Number: 814-440-3
Nikkaji: J2.717K

Properties

Computed structural properties

XLogP: -1.5
Topological polar surface area: 63.3 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 2
Rotatable bonds: 1
Heavy atoms: 5
Formal charge: 0
Complexity: 42.9

Experimental & physicochemical properties

SpringerMaterials PropertiesDensity

Physicochemical properties

Melting point: 118 · 118-120 °C (lit.)
Boiling point: 133.7 °C · 133.7°C (rough estimate)
Density: 1.415 g/cm3 · 1.415 g/cm3 (-5℃)
refractive index: 1.4264 · 1.4264 (estimate)
storage temp.: Sealed in dry,Room Temperature
pka: 13.28 · 13.28±0.10(Predicted)
form: crystalline powder
color: White
Water Solubility: 413.5 g/L · 413.5g/L(25 ºC)
InChI: InChI=1S/C2H5NO2/c3-2(5)1-4/h4H,1H2,(H2,3,5)
InChIKey: TZGPACAKMCUCKX-UHFFFAOYSA-N
SMILES: C(N)(=O)CO
FDA UNII: 18 EAK3UR7C · 18EAK3UR7C

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Safety data

PPE: Eyeshields, Gloves, type N95 (US)
wgk: 3
hs_code: 2924297099
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi
hazard_class: IRRITANT
Storage Class: 11 - Combustible Solids
Hazard statements: H302-H315-H319-H335
Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338

Chemistry & industry

Applications · 2 items

UsesGlycolamide may be used in the preparation of phosphoglycolamide.

General DescriptionGlycolamide, an isomer of glycine, can be synthesized by the ammonolysis of ethyl glycolate. The conformational analysis of glycolamide has been reported. Its diffusion coefficient in water and partial molal isothermal compressibility has been determined. Its thermodynamic properties have been investigated. Its osmotic and activity coefficients have been obtained.