HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxyacetamide
GLYCOLAMIDE · A-HYDROXYACETAMIDE · Glycolic acid amide · NSC 97323 · GlycolaMide 98% · 2-HYDROXYACETAMIDE · TIMTEC-BB SBB010080 · ALPHA-HYDROXYACETAMIDE
Identifiers & Physical Properties
| CAS No. | 598-42-5 |
|---|---|
| Molecular formula | C2H5NO2 |
| Average molar mass | 75.07 g/mol |
| Monoisotopic mass | 75.0320284 g/mol |
| SMILES | NC(=O)CO |
| InChIKey | TZGPACAKMCUCKX-UHFFFAOYSA-N |
| PubChem CID | 69021 |
| ChEBI | CHEBI:30321 |
| EC No. | 814-440-3 |
| DTXSID | DTXSID70208531 |
Chemical & Physical Properties
| XLogP | -1.5 |
|---|---|
| Topological polar surface area | 63.3 |
| Hydrogen bond donors | 2 |
| Hydrogen bond acceptors | 2 |
| Rotatable bonds | 1 |
| Heavy atoms | 5 |
| Formal charge | 0 |
| Complexity | 42.9 |
| SpringerMaterials Properties | Density |
| Melting point | 118-120 °C (lit.) |
| Boiling point | 133.7°C (rough estimate) |
| Density | 1.415 g/cm3 (-5℃) |
| Refractive index | 1.4264 (estimate) |
| Storage conditions | Sealed in dry,Room Temperature |
| pKa (acidity coefficient) | 13.28±0.10(Predicted) |
| Physical state | crystalline powder |
| Color | White |
| Solubility | 413.5g/L(25 ºC) |
| InChI | InChI=1S/C2H5NO2/c3-2(5)1-4/h4H,1H2,(H2,3,5) |
| InChIKey | TZGPACAKMCUCKX-UHFFFAOYSA-N |
| SMILES | C(N)(=O)CO |
| FDA UNII | 18EAK3UR7C |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H302-H315-H319-H335 |
| GHS precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Hazard symbols | Xi |
| Water hazard class (WGK) | 3 |
| Hazard class | IRRITANT |
| Customs code | 2924297099 |
| Storage class | 11 - Combustible Solids |
Safety & Regulations
| GHS classification | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 3 |
| Customs code | 2924297099 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | Xi |
| Hazard class | IRRITANT |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H302-H315-H319-H335 |
| GHS precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Applications & Uses
Uses
Glycolamide may be used in the preparation of phosphoglycolamide.
General Description
Glycolamide, an isomer of glycine, can be synthesized by the ammonolysis of ethyl glycolate. The conformational analysis of glycolamide has been reported. Its diffusion coefficient in water and partial molal isothermal compressibility has been determined. Its thermodynamic properties have been investigated. Its osmotic and activity coefficients have been obtained.