(2R)-2-Amino-3,3-dimethylbutan-1-ol

HCID 6932847CAS 112245-09-7
Substructure searchFind similar structures

Basic information

Standard SMILES
CC(C)(C)[C@@H](N)CO
InChIKey
JBULSURVMXPBNA-YFKPBYRVSA-N
Molecular formula
C6H15NO
Average molar mass
117.19 g/mol
Monoisotopic mass
117.1153641

Names & identifiers

Preferred name
(2R)-2-Amino-3,3-dimethylbutan-1-ol
IUPAC
(2R)-2-amino-3,3-dimethylbutan-1-ol
English name
(R)-TERT-LEUCINOL
Molecular formula
C6H15NO
Molecular weight
117.19

Names & synonyms

(2R)-2-amino-3,3-dimethylbutan-1-olRefChem:397128634-525-7112245-09-7(R)-TERT-LEUCINOLD-tert-Leucinol(R)-2-Amino-3,3-dimethylbutan-1-ol(R)-(-)-tert-LeucinolMFCD01076574H-D-Tle-olr-t-leucinol(R)-2-Amino-3,3-dimethyl-1-butanol
Show more names
D-T-LEUCINOLH-D-(TBU)GLY-OLD-T-BUTYLGLYCINOLD-ALPHA-T-BUTYLGLYCINOLD-tert-Leucinol,99%e.e.
1-Butanol, 2-amino-3,3-dimethyl-, (2R)-SCHEMBL754075AKOS015841170GS-3727EN300-1721713(R)-2-Amino-3,3-dimethyl-1-butanol, 98%, 99% ee(2R)-2-amino-3,3-dimethyl-1-butanolA802520

Database identifiers

CAS
112245-09-7
PubChem CID
6932847
DTXSID
DTXSID60426146
EC Number
634-525-7
Nikkaji
J1.052.699J

Properties

Computed structural properties

XLogP
0.4
Topological polar surface area
46.3 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
2
Rotatable bonds
2
Heavy atoms
8

Physicochemical properties

Melting point
30 · 30-33 °C(lit.)
Boiling point
70 °C0.4 · 70 °C0.4 mm Hg(lit.)
Density
0.9 g/mL · 0.9 g/mL at 25 °C(lit.)
Flash point
194 °F · 194 °F
storage temp.
2 · Keep in dark place,Inert atmosphere,2-8°C
form
Liquid

Safety & regulation

GHS classification

GHS Classification · 5 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (100%)

Safety data

PPE
dust mask type N95 (US), Eyeshields, Gloves
wgk
3
hs_code
2922190090
risk_code
36/37/38
Signal word
Warning
Symbol(GHS)
GHS07

Chemistry & industry

Applications · 1 item

Uses(R)-Tert-leucinol (H-D-Tle-ol) is a chiral molecular compound with optical activity and its enantiomeric form is (S)-tert-leucinol. (R)-Tert-leucinol belongs to the class of α-amino alcohols, which have certain biological activities and are potent reversible inhibitors of protein synthesis. (R)-Tert-leucinol can be used as a chiral ligand for asymmetric catalytic reactions. Its derivatives are also used as optical splitting reagents, for peptidyl alcohol synthesis in peptide drugs, and as inhibitors of protein hydrolysis.

Upstream & downstream products

Suppliers50 total

郑州阿尔法化工有限公司+86-18530059196 · [email protected]
苏州道澜生物医药科技有限公司15952404857 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
山东旭晨化工科技有限公司0533-15715337262 15715337262 · [email protected]
上海凌富药物研究有限公司+86(21)5895 0110 19945755304 · [email protected]

Related reactions

2 records
New reaction record

Linked notes

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