Basic information
- CAS
6138-47-2- Standard SMILES
Cl.N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O- InChIKey
HFEMPWKWYHWPQX-YDALLXLXSA-N- Molecular formula
- C15H13ClI3NO4
- Average molar mass
- 687.43 g/mol
- Monoisotopic mass
- 686.7667
Names & identifiers
- Preferred name
- Liothyronine hydrochloride
- IUPAC
- (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid;hydrochloride
- English name
- O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine hydrochloride
- Molecular formula
- C15H13ClI3NO4
- Molecular weight
- 687.43443
Names & synonyms
Liothyronine hydrochlorideLiothyronine HCl6138-47-2T66DHO0SETLiothyronine (hydrochloride)O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine hydrochloride(S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid hydrochloride(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid;hydrochlorideUNII-T66DHO0SETThyrotradin (TN)EINECS 228-120-06138-47-2 (HCl)
Show more names
Liotironina3,3',5-Triiodo-L-thyronineHCl3,3',5-Triiodo-L-thyroninehydrochloride
Triiodothyronine hydrochlorideSCHEMBL438744tri-iodothyronine hydrochlorideorb1706750HY-A0070CDTXSID10210299HFEMPWKWYHWPQX-YDALLXLXSA-NL-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, hydrochloride
Database identifiers
- CAS
6138-47-2- PubChem CID
- 71283
- DTXSID
DTXSID10210299- UNII
- T66DHO0SET
- EC Number
- 228-120-0
Properties
Computed structural properties
- Topological polar surface area
- 92.8 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 402
Physicochemical properties
- alpha
- 29.5 · D29.5 +21.5° (c = 4.75 in a mixture of 1 vol N HCl and 2 vols ethanol)
- FDA UNII
- 66 DHO0SET · T66DHO0SET
Chemistry & industry
Applications
UsesLiothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1][2][3].
Suppliers6 total
陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
上海稳同科技有限公司02151600108 13062666369 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
青岛腾龙微波科技有限公司0532-83818797 17669478191 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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