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2-Ethoxyethyl methacrylate

HCID 71404
NotesReactions
Basic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
Substructure searchFind similar structures

Basic information

CAS
2370-63-0
Standard SMILES
C=C(C)C(=O)OCCOCC
InChIKey
SFPNZPQIIAJXGL-UHFFFAOYSA-N
Molecular formula
C8H14O3
Average molar mass
158.19 g/mol
Monoisotopic mass
158.0942943

Overview

Based on available data, the CIR Expert Panel concluded that ... Ethoxyethyl Methacrylate is safe as used in nail enhancement products when skin contact is avoided. Products containing these ingredients should be accompanied with directions to avoid skin contact, because of the sensitizing potential of Methacrylates.

Names & identifiers

Preferred name
2-Ethoxyethyl methacrylate
IUPAC
2-ethoxyethyl 2-methylprop-2-enoate
English name
2-Ethoxyethyl Methacrylate
Molecular formula
C8H14O3
Molecular weight
158.2

Names & synonyms

2-Ethoxyethyl methacrylate2370-63-0Ethoxyethyl methacrylate2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester2-ethoxyethyl 2-methylprop-2-enoateMethacrylic acid, 2-ethoxyethyl ester2-Ethoxyethyl Methacrylate (stabilized with MEHQ)5Q6XR4MR8EETHOXYETHYLMETHACRYLATENSC 2416251289-08-8DTXSID1022186
Show more names
EEMAEoEMACHLUMICRYI EEMA2-EthoxyethylmethacrylatEthoxyethyl methacrylate EEMA2-Ethoxyethyl 2-methylacrylate
ACRYESTER ETstarbld0019598MFCD00009249NSC-241622-(ethyloxy)ethyl 2-methylprop-2-enoateEthylene Glycol Monoethyl Ether Methacrylate2-Ethoxyethyl 2-methylacrylate #NSC24162

Database identifiers

CAS
2370-63-0
PubChem CID
71404
DTXSID
DTXSID1022186
ChEMBL

Properties

Computed structural properties

XLogP
1.4
Topological polar surface area
35.5 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
3
Rotatable bonds
6
Heavy atoms
11
Formal charge
0
Complexity
140

Experimental & physicochemical properties

PolymersPlastics & Rubber -> (Meth)acrylates
CosmeticsCosmetic ingredients (Ethoxyethyl Methacrylate) -> CIR (Cosmetic Ingredient Review)
Vapor Pressure1.1 [mmHg]
Physical Description · 2 items

Liquid

Colorless liquid with a fruity odor; [Atofina MSDS]

Physicochemical properties

Melting point
25 °C · <25 °C
Boiling point
91 · 91-93 °C/35 mmHg (lit.)
Density
0.964 g/mL · 0.964 g/mL at 25 °C (lit.)
vapor pressure
1.5 hPa · 1.5 hPa (20 °C)
refractive index
20 · n20/D 1.429(lit.)
Flash point
161 °F · 161 °F
storage temp.
2 · 2-8°C
solubility
13 g/l · 13g/l

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 6 items

Danger

H315 (23.8%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 172 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H227: Combustible liquid [Warning Flammable liquids]

Hazard information

Regulatory Information · 4 items

Chemical: 2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester

2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

REACH registered substance: 2-ethoxyethyl methacrylate (EC: 219-135-3)

2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - 2-Methoxyethyl methacrylate and 2-ethoxyethyl methacrylate
Hazards SummaryStabilized with 500 ppm butylated hydroxytoluene (CAS# 128-37-0); Causes essentially no eye and mild skin irritation in rabbits; Not a skin sensitizer in guinea pigs; [Atofina MSDS] See n-Butyl methacrylate.
Hazard Classes and Categories · 2 items

Skin Irrit. 2 (23.8%)

Flammable liquids - Category 4

Chemistry & industry

Uses & manufacturing

Uses · 2 items

CIR ingredient: Ethoxyethyl Methacrylate

Used as an intermediate; [Atofina MSDS]

U.S. Production2023: <50,000 lb
Industry UsesMonomers
General Manufacturing Information · 2 items

Pharmaceutical and Medicine Manufacturing

2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester: ACTIVE

Applications

UsesThe free-radical initiated copolymerizations of methyl methacrylate (MMA) with 2-Ethoxyethyl Methacrylate (2-EOEMA) were carried out by Manju et al. using 2,2-azo-bisisobutyronitrile (AIBN) as the initiator in 1,4-dioxane solutions[1].

Upstream & downstream products

Upstream raw materials

Propanoic acid, 2-methoxy-2-methyl-, methyl esterAcetone cyanohydrin2-Ethoxyethanolcarbon monoxideMethyl methacrylateAlleneMethacryloyl chloride

Suppliers100 total

梯希爱(上海)化成工业发展有限公司

Related reactions

5 records
New reaction record
HRID 483331 reaction equation
HRID 483331As productuspto-grants-1993_07
HRID 1029353 reaction equation
HRID 1029353As productuspto-grants-1992_04
HRID 1034131 reaction equation
HRID 1034131As productuspto-grants-1994_05
HRID 1604197 reaction equation
HRID 1604197As productuspto-grants-1999_11
HRID 1604198 reaction equation
HRID 1604198As productuspto-grants-1999_11

Compound notes

Loading…

On this pageBasic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
CHEMBL1414186
UNII
5Q6XR4MR8E
EC Number
219-135-3
Nikkaji
J109.532C
form
Oil
color
Colourless
Specific Gravity
0.966 · 0.966
Viscosity
5 cp · 5 cp (25C)
Water Solubility
17.05 g/L · 17.05g/L at 20℃
Stability
Light Sensitive
Cosmetic Ingredient Review (CIR)
2 · 2-Ethoxyethyl Methacrylate (2370-63-0)
InChI
1S/C8H14O3/c1-4-10-5-6-11-8(9)7(2)3/h2,4-6H2,1,3H3
InChIKey
SFPNZPQIIAJXGL-UHFFFAOYSA-N
SMILES
CCOCCOC(=O)C(C)=C
LogP
1.8 at · 1.8 at 23.3℃
CAS DataBase Reference
2370 · 2370-63-0(CAS DataBase Reference)
EWG's Food Scores
2 · 2-5
FDA UNII
5 Q6XR4MR8E · 5Q6XR4MR8E
EPA Substance Registry System
2 · 2-Ethoxyethyl methacrylate (2370-63-0)
UNSPSC Code
12352108 · 12352108
NACRES
23 · NA.23
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
335 · H335-H412
Precautionary statements
261 · P261-P271-P273-P304+P340+P312-P403+P233-P405
target organs
Respiratory system
PPE
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes
Xi
Risk Statements
36 · 36/37/38
Safety Statements
26 · 26-27-36/37/39
WGK Germany
2 · 2
Autoignition Temperature
209 °C · 209 °C
TSCA
TSCA listed
HS Code
29161400 · 29161400
Storage Class
10 · 10 - Combustible liquids
Hazard Classifications
3 STOT · Aquatic Chronic 3STOT SE 3
Toxicity
50 orally · LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 2000 mg/kg
REACH Registrations
Active

Safety & protection

Protective Action Criteria (PAC) · 3 items

200 [mg/m3]

2200 [mg/m3]

13000 [mg/m3]

Toxicology

Toxicity Summary · 2 items

Based on available data, the CIR Expert Panel concluded that ... Ethoxyethyl Methacrylate is safe as used in nail enhancement products when skin contact is avoided. Products containing these ingredients should be accompanied with directions to avoid skin contact, because of the sensitizing potential of Methacrylates.

Safe for use in cosmetics, with qualifications

Safety data

PPE
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk
2
tsca
TSCA listed
hs_code
29161400
Toxicity
LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 2000 mg/kg
risk_code
36/37/38
Signal word
Warning
Symbol(GHS)
GHS07
hazard_code
Xi
safety_code
26-27-36/37/39
Storage Class
10 - Combustible liquids
target organs
Respiratory system
Hazard statements
H335-H412
REACH Registrations
Active
Hazard Classifications
Aquatic Chronic 3STOT SE 3
Autoignition Temperature
209 °C
Precautionary statements
P261-P271-P273-P304+P340+P312-P403+P233-P405
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