Basic information
- CAS
33237-74-0- Standard SMILES
CCN(CC)CCCN(c1ccccc1)C1Cc2ccccc2C1.Cl- InChIKey
KIPFVRHNAAZJOD-UHFFFAOYSA-N- Molecular formula
- C22H31ClN2
- Average molar mass
- 358.9 g/mol
- Monoisotopic mass
- 358.2175767
Overview
Aprindine hydrochloride is a member of indanes.
Names & identifiers
- Preferred name
- Aprindine Hydrochloride
- IUPAC
- N'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N'-phenylpropane-1,3-diamine;hydrochloride
- English name
- APRINDINE HCL
- Molecular formula
- C22H31ClN2
- Molecular weight
- 358.95
Names & synonyms
aprindine hydrochlorideAprindine HCl33237-74-0AspenonRitmusinCompound 83846Aprinidine chlorideLilly 83846CCRIS 5480DTXSID5046726PB5EKT7Q2VAprindine hydrochloride [USAN:JAN]
Show more names
fiboranFibocilAmidonalAprindinaAPRINDINE HCL ISO 9001：2015 REACH
EINECS 251-418-7Aspenon (TN)COMPOUND-83846NSC 284614MS 5075MS-5075NSC-284614DTXCID3026726
Database identifiers
- CAS
33237-74-0- PubChem CID
- 71413
- DTXSID
DTXSID5046726- ChEMBL
CHEMBL2104501- ChEBI
CHEBI:31229- UNII
- PB5EKT7Q2V
- EC Number
- 251-418-7
Properties
Computed structural properties
- Topological polar surface area
- 6.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 8
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 332
Physicochemical properties
- Melting point
- 120 · 120-121°
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: >10mg/mL
- form
- solid
- color
- Light Brown to Brown
- Water Solubility
- 2 O: · H2O: >10mg/mL
- Stability
- Hygroscopic
- InChI
- InChI=1S/C22H30N2.ClH/c1-3-23(4-2)15-10-16-24(21-13-6-5-7-14-21)22-17-19-11-8-9-12-20(19)18-22;/h5-9,11-14,22H,3-4,10,15-18H2,1-2H3;1H
- InChIKey
- KIPFVRHNAAZJOD-UHFFFAOYSA-N
- SMILES
- C1(CC2C=CC=CC=2C1)N(CCCN(CC)CC)C1C=CC=CC=1.Cl
- FDA UNII
- 5 EKT7Q2V · PB5EKT7Q2V
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 77 · NA.77
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- rtecs
- TX7386000
- risk_code
- 22-36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- safety_code
- 26
- Storage Class
- 11 - Combustible Solids
- target organs
- Respiratory system
- Hazard statements
- H302-H315-H319-H335
- Hazard Classifications
- Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Applications
UsesAprindine is a long-acting antiarrhythmic agent, effective when administered orally or intravenously in the treatment of ventricular arrhythmias of varying etiologies.
Upstream & downstream products
Upstream raw materials
Suppliers28 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
湖北海克斯生化有限公司17362916295; 17362916295 · [email protected]
湖北海克斯生化有限公司18696113233 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
湖北辰心化工有限公司18696113233 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
玺标（上海）科技有限公司18512111473 18512111473 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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