CAS 59983-39-0 (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine (HCID 7156993)

Substructure search Find similar structures

Basic information

CAS: 59983-39-0
Standard SMILES: COC[C@@H]1CCCN1N
InChIKey: BWSIKGOGLDNQBZ-LURJTMIESA-N
Molecular formula: C6H14N2O
Average molar mass: 130.19 g/mol

Names & identifiers

Preferred name: (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine
IUPAC: (2S)-2-(methoxymethyl)pyrrolidin-1-amine
English name: (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine
Molecular formula: C6H14N2O
Molecular weight: 130.19

Names & synonyms

59983-39-0(S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine1-Pyrrolidinamine, 2-(methoxymethyl)-, (2S)-[S]-(-)-1-amino-2-(methoxymethyl)pyrrolidineRefChem:407659672-763-3(S)-2-(Methoxymethyl)pyrrolidin-1-amineSAMP(2S)-2-(methoxymethyl)pyrrolidin-1-amine(S)-1-Amino-2-(methoxymethyl)pyrrolidineMFCD00064485SCHEMBL1203933

Show more names

ENDERS REAGENTS-ENDERS REAGENT2-(Methoxymethyl)-1-pyrrolidinamine(S) 1-AMINO-2-METHOXYMETHYLPYRROLIDINE(S)-(-)-1-AMINO-2-(METHOXYMETHYL)PYRROLI(2S)-1-Amino-2-(methoxymethyl)pyrrolidine

AKOS015855056AS-64519(S)-N-amino-2-(methoxymethyl)pyrrolidine(S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine, 95%2-(Methoxymethyl)-1-pyrrolidinamine #AM9645(S)-(-)-1-Amino-2-(methoxymethyl)-pyrrolidine(2S)-2-(methoxymethyl)-1-pyrrolidinamine

Database identifiers

CAS: 59983-39-0
PubChem CID: 7156993
EC Number: 672-763-3
Nikkaji: J90.076A

Properties

Computed structural properties

XLogP: -0.1
Topological polar surface area: 38.5 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 3
Rotatable bonds: 2
Heavy atoms: 9
Formal charge: 0
Complexity: 87.1

Experimental & physicochemical properties

Chemical ClassesNitrogen Compounds -> Other Nitrogen Compounds

Physical DescriptionClear, light yellow liquid; [Aldrich MSDS]

Physicochemical properties

Boiling point: 42 °C1.8 · 42 °C1.8 mm Hg(lit.)
Density: 0.97 g/mL · 0.97 g/mL at 25 °C(lit.)
refractive index: 20 · n20/D 1.465(lit.)
Flash point: 162 °F · 162 °F
storage temp.: 2 · Keep in dark place,Inert atmosphere,2-8°C
pka: 7.93 · 7.93±0.40(Predicted)
form: Liquid
color: Colorless to Almost colorless
optical activity: 20 · [α]20/D 79°, neat
Water Solubility: 2 O, · sol H2O, ether, dichloromethane.
BRN: 1523794 · 1523794

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information1-Pyrrolidinamine, 2-(methoxymethyl)-, (2S)-: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryMay cause irritation; [Aldrich MSDS] See Pyrrolidine.

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Safety data

F: 10-23
PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 3
hs_code: 29339980
Signal word: Warning
Symbol(GHS): GHS07
safety_code: 23-24/25
Storage Class: 10 - Combustible liquids
Hazard statements: H302
Precautionary statements: P280-P305+P351+P338

Chemistry & industry

Applications · 2 items

Uses(S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine is a disubstituted pyrrolidine. (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine undergoes condensation reactions with carbonyl compounds to produce hydrazones which are useful for highly enantioselective synthesis.

UsesUndergoes condensation reactions with carbonyl compounds to produce hydrazones which are useful synthons in highly enantioselective syntheses.