2-Amino-4-methylthiazole

HCID 74143CAS 1603-91-4
Substructure searchFind similar structures

Basic information

Standard SMILES
Cc1csc(N)n1
InChIKey
OUQMXTJYCAJLGO-UHFFFAOYSA-N
Molecular formula
C4H6N2S
Average molar mass
114.17 g/mol
Monoisotopic mass
114.02516919

Names & identifiers

Preferred name
2-Amino-4-methylthiazole
IUPAC
4-methyl-1,3-thiazol-2-amine
English name
2-Amino-4-methylthiazole
Molecular formula
C4H6N2S
Molecular weight
114.17

Names & synonyms

2-Amino-4-methylthiazole1603-91-42-Thiazolamine, 4-methyl-4-Methyl-1,3-thiazol-2-amineaminomethiazole4-METHYL-2-THIAZOLAMINENormotiroide2-amino-4-methyl-1,3-thiazoleNomortiroide4-Methyl-2-thiazolylamine4-Methylthiazol-2-ylamineEINECS 216-505-6
Show more names
24TTIMTEC-BB SBB004307Mirabelon Impurity 45AMino-4-MethylthiazoleLABOTEST-BB LT000806444-metyl-2-thiazolamine
NSC-40462AI3-61054R95713542RDTXSID40166856NSC 404622-AMINO-4-METHYLTHIAZOLE [MI]RefChem:464352DTXCID6089347

Database identifiers

CAS
1603-91-4
PubChem CID
74143
DTXSID
DTXSID40166856
ChEMBL
CHEMBL505019
UNII
R95713542R
EC Number
216-505-6
Nikkaji
J568A

Properties

Computed structural properties

XLogP
1
Topological polar surface area
67.2 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
3
Rotatable bonds
0
Heavy atoms
7

Experimental & physicochemical properties

SpringerMaterials Properties15N nuclear magnetic resonance spectrum
Solubility10.8 [ug/mL] (The mean of the results at pH 7.4)

Physicochemical properties

Melting point
44 · 44-47 °C (lit.)
Boiling point
231 · 231-232 °C (lit.)
Density
1.176 · 1.176 (estimate)
refractive index
1.5 · 1.5000 (estimate)
Flash point
230 °F · >230 °F
storage temp.
Keep in dark place,Sealed in dry,Room Temperature

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (15.2%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 46 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 2 items

Chemical: 2-Thiazolamine, 4-methyl-

2-Thiazolamine, 4-methyl-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesAcute Tox. 4 (15.2%)

Safety data

PPE
dust mask type N95 (US), Eyeshields, Gloves
wgk
3
hs_code
29341000
risk_code
36/37/38-36/37-22-20/21/22
Signal word
Warning
Symbol(GHS)
GHS07

Chemistry & industry

Applications · 1 item

UsesThis study developed a series of novel 2-amino-4-methylthiazole analogues for combating Gram-positive bacterial, Gram-negative bacterial, and fungal infections[1]. 2-Amino-4-methylthiazole serves as a corrosion inhibitor for electrogalvanized steel in 0.1 M neutral NaCl solution[2].

Upstream & downstream products

Suppliers50 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]
上海凯曼化工科技有限公司021-021-50400622 15618790390 · [email protected]

Related reactions

293 records
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Linked notes

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