Cyclopropanecarbonyl chloride (HCID 77637)

Names & identifiers

Preferred name: Cyclopropanecarbonyl chloride
IUPAC: cyclopropanecarbonyl chloride
English name: Cyclopropanecarbonyl Chloride
Molecular formula: C4H5ClO
Molecular weight: 104.53

Names & synonyms

Cyclopropanecarbonyl chlorideCyclopropanecarboxylic acid chlorideCyclopropane carbonyl chlorideCyclopropylcarboxyl chloridecyclopropane carboxylic acid chlorideEINECS 223-684-4DTXSID2063266EC 223-684-4RefChem:129929DTXCID9039735223-684-4ZOOSILUVXHVRJE-UHFFFAOYSA-N

Show more names

CPCCICyclopropanecarbonylCPA-ClopropanecarbonyLArtemether Impurity 12Cyclopropylformyl chloride

4023-34-1Cyclopropanoyl chloridecyclopropylcarbonyl chlorideCyclopropyl carboxylic chloridecyclopropylcarboxylic acid chloridecyclopropane-d5-carbonyl chloridecyclopropyl carbonyl chlorideCyclopropylbenzoyl chloride

Database identifiers

CAS: 4023-34-1
PubChem CID: 77637
DTXSID: DTXSID2063266
UNII: 6J5U4R2KAF
EC Number: 223-684-4
Nikkaji: J23.515F

Properties

Computed structural properties

XLogP: 1.2
Topological polar surface area: 17.1 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 1
Rotatable bonds: 1
Heavy atoms: 6
Formal charge: 0
Complexity: 75.6

Experimental & physicochemical properties

SpringerMaterials PropertiesSchoenflies notation

Physicochemical properties

Melting point: 77.5 · 77.5-78.5 °C(Solv: hexane (110-54-3))
Boiling point: 119 °C · 119 °C(lit.)
Density: 1.152 g/mL · 1.152 g/mL at 25 °C(lit.)
refractive index: 20 · n20/D 1.452(lit.)
Flash point: 74 °F · 74 °F
storage temp.: 2 · 2-8°C
solubility: soluble in Chloroform
form: Liquid
Specific Gravity: 1.152 · 1.1520
color: Clear colorless to slightly yellow
Water Solubility: decomposes
Sensitive: Moisture Sensitive
BRN: 471286 · 471286
Stability: Moisture Sensitive
InChI: 1S/C4H5ClO/c5-4(6)3-1-2-3/h3H,1-2H2
InChIKey: ZOOSILUVXHVRJE-UHFFFAOYSA-N
SMILES: ClC(=O)C1CC1
CAS DataBase Reference: 4023 · 4023-34-1(CAS DataBase Reference)
NIST Chemistry Reference: Cyclopropanecarboxylic acid chloride(4023-34-1)
EPA Substance Registry System: Cyclopropanecarbonyl chloride (4023-34-1)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 2 · GHS02,GHS05,GHS06
Signal word: Danger
Hazard statements: 226 · H226-H301-H314
Precautionary statements: 210 · P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes: C,F
Risk Statements: 10 · 10-34-29-25-36-38
Safety Statements: 26 · 26-36/37/39-45-8-16
RIDADR: 2920 · UN 2920 8/PG 2
WGK Germany: 3 · 3
F: 10 · 10-21
TSCA: TSCA listed
HazardClass: 8 · 8
PackingGroup: II
HS Code: 29162000 · 29162000
Storage Class: 3 · 3 - Flammable liquids
Hazard Classifications: 3 OralEye · Acute Tox. 3 OralEye Dam. 1Flam. Liq. 3Skin Corr. 1B
Toxicity: 50 orally · LD50 orally in Rabbit: 200 mg/kg
REACH Registrations: Active
Limited Quantities: 1 L · 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H226 (86.3%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P234, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P363, P370+P378, P390, P403+P233, P403+P235, P405, P406, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 270 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 3 items

Chemical: Cyclopropanecarbonyl chloride

Status: Active Update: 12-10-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/11347

Cyclopropanecarboxylic acid chloride: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesFlam. Liq. 3 (86.3%)

Safety data

F: 10-21
PPE: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk: 3
tsca: TSCA listed
ridadr: UN 2920 8/PG 2
hs_code: 29162000
Toxicity: LD50 orally in Rabbit: 200 mg/kg
risk_code: 10-34-29-25-36-38
Signal word: Danger
Symbol(GHS): GHS02,GHS05,GHS06
hazard_code: C,F
safety_code: 26-36/37/39-45-8-16
hazard_class: 8
Storage Class: 3 - Flammable liquids
packing_group: II
Hazard statements: H226-H301-H314
Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
REACH Registrations: Active
Hazard Classifications: Acute Tox. 3 OralEye Dam. 1Flam. Liq. 3Skin Corr. 1B
Precautionary statements: P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338

Chemistry & industry

Uses & manufacturing

General Manufacturing InformationCyclopropanecarbonyl chloride: ACTIVE

Applications · 1 item

UsesCyclopropanecarbonyl chloride can be used as an alkylating reagent in the preparation of some chemical building blocks such as formylcyclopropane, cyclopropanecarboxylic acid hydrazide, bis(cyclopropylcarbonyl) peroxide, 1-cyclopropanecarboxamide, 2-cyclopropylcarbonylcyclohexane-1,3-diones and cyclopropyl analog of triazolopiperazine-amides.