HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Chloromethyl)cyclopropane
(CHLOROMETHYL)CYCLOPROPANE · CPMCl · TEDI-003 · Einecs 227-632-1 · Cylopropylmethyl chl · Desidustat Impurity 67 · cylopropylMethyl loride · Cyclopropylmethychloride
Identifiers & Physical Properties
| CAS No. | 5911-08-0 |
|---|---|
| Molecular formula | C4H7Cl |
| Average molar mass | 90.55 g/mol |
| Monoisotopic mass | 90.0236279 g/mol |
| SMILES | ClCC1CC1 |
| InChIKey | ZVTQWXCKQTUVPY-UHFFFAOYSA-N |
| PubChem CID | 80013 |
| EC No. | 227-632-1 |
| DTXSID | DTXSID40207854 |
Chemical & Physical Properties
| XLogP | 1.6 |
|---|---|
| Topological polar surface area | 0 |
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 0 |
| Rotatable bonds | 1 |
| Heavy atoms | 5 |
| Formal charge | 0 |
| Complexity | 30.6 |
| SpringerMaterials Properties | Schoenflies notation |
| Melting point | -91°C |
| Boiling point | 87-89 °C(lit.) |
| Density | 0.98 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.435(lit.) |
| Flash point | 29 °F |
| Storage conditions | Inert atmosphere,2-8°C |
| Solubility | soluble in Chloroform, MethanolNot miscible in water. |
| Physical state | clear liquid |
| Color | Colorless to Almost colorless |
| BRN | 635697 |
| InChI | InChI=1S/C4H7Cl/c5-3-4-1-2-4/h4H,1-3H2 |
| InChIKey | ZVTQWXCKQTUVPY-UHFFFAOYSA-N |
| SMILES | C1(CCl)CC1 |
| CAS DataBase Reference | 5911-08-0(CAS DataBase Reference) |
| FDA UNII | J7OKQCC0KW |
| NIST Chemistry Reference | (Chloromethyl)cyclopropane(5911-08-0) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
| GHS pictogram | GHS02,GHS07 |
| Signal word | Danger |
| GHS hazard statements | H225-H315-H319-H335 |
| GHS precautionary statements | P210-P302+P352-P305+P351+P338 |
| Target organs | Respiratory system |
| Personal protective equipment (PPE) | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard symbols | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
| UN transport number | UN 1993 3/PG 2 |
| Water hazard class (WGK) | 3 |
| Hazard class | 3Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 3 |
| Packing group | II |
| Customs code | 29035990 |
| Storage class | 3 - Flammable liquids |
| REACH registrations | Active |
| Limited quantities | 1.0 L (0.3 gallon) (liquid) |
| Excepted quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
Safety & Regulations
| GHS classification | DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 50 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatory information | Chemical: Cyclopropane, (chloromethyl)-Status: Active Update: 29-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23460Cyclopropyl methyl chloride: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Flam. Liq. 2 (100%) |
| Personal protective equipment (PPE) | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Water hazard class (WGK) | 3 |
| UN transport number | UN 1993 3/PG 2 |
| Customs code | 29035990 |
| Risk statements (R) | 11-36/37/38 |
| Signal word | Danger |
| GHS pictogram | GHS02,GHS07 |
| Hazard symbols | F,Xi |
| Safety statements (S) | 16-26-36/37/39 |
| Hazard class | 3Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 3 |
| Storage class | 3 - Flammable liquids |
| Packing group | II |
| Target organs | Respiratory system |
| GHS hazard statements | H225-H315-H319-H335 |
| Limited quantities | 1.0 L (0.3 gallon) (liquid) |
| Excepted quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) |
| REACH registrations | Active |
| GHS precautionary statements | P210-P302+P352-P305+P351+P338 |
Applications & Uses
Uses
(Chloromethyl)cyclopropane was used in the synthesis of (lithiomethyl)cyclopropane and homoallyllithium via 4,4′-di-tert-butylbiphenyl or naphthalene-catalysed lithiation reaction.
General Description
(Chloromethyl)cyclopropane on reaction with isolable dialkylsilylene affords 5-silaspiro[4.4]nonane derivative.