1,4-Bis(3-aminopropyl)piperazine

HCID 81629CAS 7209-38-3

Basic information

Standard SMILES
NCCCN1CCN(CCCN)CC1
InChIKey
XUSNPFGLKGCWGN-UHFFFAOYSA-N
Molecular formula
C10H24N4
Average molar mass
200.32 g/mol
Monoisotopic mass
200.20009678

Names & identifiers

Preferred name
1,4-Bis(3-aminopropyl)piperazine
IUPAC
3-[4-(3-aminopropyl)piperazin-1-yl]propan-1-amine
English name
1,4-Bis(3-aminopropyl)piperazine
Molecular formula
C10H24N4
Molecular weight
200.32

Names & synonyms

1,4-Bis(3-aminopropyl)piperazineRefChem:4170327209-38-31,4-Piperazinedipropanamine3,3'-(Piperazine-1,4-diyl)bis(propan-1-amine)Bis(aminopropyl)piperazineN,N'-Bis(3-aminopropyl)piperazine3-[4-(3-aminopropyl)piperazin-1-yl]propan-1-amineMFCD00006161CCRIS 8915EINECS 230-589-1UNII-7GVX6C734B
Show more names
BAPPRZLABOTEST-BB LT00454560BIS AMINOPROPYL PIPIRAZINE1,4-PIPERAZINEBIS(PROPYLAMINE)1,4-(BIS AMINOPROPYL) PIPERAZINE
7GVX6C734BDTXSID8022246Piperazine, 1,4-bis(3-aminopropyl)-N,N'-Bis(p-aminopropyl)piperazine1,4-Bis(3-aminoprop-1-yl)piperazine1 pound not4-Bis(3-aminopropyl)piperazine1,4-Di(3-aminopropyl)piperazineBAPP

Database identifiers

CAS
7209-38-3
PubChem CID
81629
DTXSID
DTXSID8022246
ChEMBL
CHEMBL41307
UNII
7GVX6C734B
EC Number
230-589-1
Nikkaji
J2.148.520I、J35.447C

Properties

Computed structural properties

XLogP
-1.4
Topological polar surface area
58.5 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
4
Rotatable bonds
6
Heavy atoms
14

Experimental & physicochemical properties

Physical DescriptionLiquid
Collision Cross Section150.3 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID8022246];150.2 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID8022246]

Physicochemical properties

Melting point
15 °C · 15 °C(lit.)
Boiling point
150 · 150-152 °C2 mm Hg(lit.)
Density
0.973 g/mL · 0.973 g/mL at 25 °C(lit.)
vapor density
6.9 · 6.9 (vs air)
vapor pressure
0.133 Pa · 0.133Pa at 25℃
refractive index
20 · n20/D 1.502(lit.)

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H302 (58.3%): Harmful if swallowed [Warning Acute toxicity, oral];H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation];H318 (78.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H412 (58.3%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P260, P264, P264+P265, P270, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 206 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 5 items

Chemical: 1,4-Piperazinedipropanamine;Specific Information Requirement: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

1,4-Piperazinedipropanamine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,4-Piperazinedipropanamine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 19-08-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/21266

1,4-Bis(3-aminopropyl)piperazine: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Hazard Classes and Categories · 2 items

Acute Tox. 4 (58.3%);Skin Corr. 1B (100%);Eye Dam. 1 (78.2%);Aquatic Chronic 3 (58.3%)

Corrosives

Regulatory information

Regulatory Information · 5 items

Chemical: 1,4-Piperazinedipropanamine;Specific Information Requirement: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

1,4-Piperazinedipropanamine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,4-Piperazinedipropanamine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 19-08-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/21266

1,4-Bis(3-aminopropyl)piperazine: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Safety data

PPE
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
wgk
3
tsca
TSCA listed
rtecs
TK8700000
ridadr
UN 2735 8/PG 2
hs_code
2933599590

Chemistry & industry

Uses & manufacturing

U.S. Production2023: 46,914 lb;2022: 50,684 lb;2021: 51,940 lb
Industry UsesAdhesion/cohesion promoter
General Manufacturing Information · 2 items

Adhesive Manufacturing

1,4-Piperazinedipropanamine: ACTIVE

Applications

Uses1,4-Bis(3-aminopropyl)piperazine was used to functionalize natural montmorillonite (M) and synthetic kanemite (K)1.

General DescriptionThe thermodynamic parameters for protonation of 1,4-bis(3-aminopropyl)-piperazine (BAPP) were studied in aqueous solution using a potentiometric technique.

Upstream & downstream products

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
常州帝通化工有限公司+86-0519-88298848 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]

Related reactions

24 records

Linked notes

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