1,4-Bis(3-aminopropyl)piperazine → (3-Chloropropanoyl)urea

HRID 973135

Reaction equation

HRID 973135 reaction equation
[NH2:1]CCCN1CCN(CCCN)CC1.[Cl:15][CH2:16][CH2:17][C:18]([N:20]=[C:21]=[O:22])=[O:19]>>[Cl:15][CH2:16][CH2:17][C:18]([NH:20][C:21]([NH2:1])=[O:22])=[O:19]

Participants

3

Reactant 2

HCID 816291,4-Bis(3-aminopropyl)piperazineHCID 135723743-Chloropropanoyl isocyanate

Product 1

HCID 12937417(3-Chloropropanoyl)ureaYield 318.8%

Procedure

In the same way as in Example 1, reaction of 10.0 g (50 mmols) of N,N'-bis(3-aminopropyl)piperazine with 14.3 g (106 mmols) of 3-chloropropionyl isocyanate gives 24.0 g of the 3-chloropropionylurea compound of the formula ##STR11##

Sources & evidence

ORD record
ord-b96a6483b0914c7fbe56c2cf803e7456
Source dataset
uspto-grants-1977_10
Patent number
US04055431

Linked notes

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