2-Chloropyridin-4-amine

HCID 84432

Basic information

CAS
14432-12-3
Standard SMILES
Nc1ccnc(Cl)c1
InChIKey
BLBDTBCGPHPIJK-UHFFFAOYSA-N
Molecular formula
C5H5ClN2
Average molar mass
128.56 g/mol
Monoisotopic mass
128.01412584

Overview

4-Amino-2-chloropyridine is an aminopyridine.

Names & identifiers

Preferred name
2-Chloropyridin-4-amine
IUPAC
2-chloropyridin-4-amine
English name
4-Amino-2-chloropyridine
Molecular formula
C5H5ClN2
Molecular weight
128.56

Names & synonyms

4-Amino-2-chloropyridine14432-12-32-Chloropyridin-4-amine4-Pyridinamine, 2-chloro-BHC29VF8KHEINECS 238-403-0(2-CHLOROPYRIDIN-4-YL)AMINEDTXSID20162674RefChem:470506DTXCID0085165238-403-02-Chloro-4-aminopyridine
Show more names
2-CHLORO-4-AMINOPVRIDINEAMINO-2-CHLOROPYRIDINE, 4-2-CHLORO-4-AMINOPYRIDINE 97%Intermediate of Forchlorfenuroncas 14432-12-3cppu intermediateoropyridin-4-aminebuy cas 14432-12-3
2-Chloro-pyridin-4-ylamine2-Chloro-4-pyridinamineMFCD000600892-chloro-4-pyridylamine2-chloro-4-amino pyridine4-amino-2-chloro pyridineAKOS001407522EN300-25778

Database identifiers

CAS
14432-12-3
PubChem CID
84432
DTXSID
DTXSID20162674
ChEBI
CHEBI:177030
UNII
BHC29VF8KH
EC Number
238-403-0
Nikkaji
J81.768F

Properties

Computed structural properties

XLogP
1.1
Topological polar surface area
38.9 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
2
Rotatable bonds
0
Heavy atoms
8

Physicochemical properties

Melting point
90 · 90-94 °C(lit.)
Boiling point
153 °C · 153°C 5mm
Density
1.2417 · 1.2417 (rough estimate)
refractive index
1.511 · 1.5110 (estimate)
Flash point
153 °C/5mm · 153°C/5mm
storage temp.
Keep in dark place,Sealed in dry,Room Temperature

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (15.1%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 53 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory InformationCommission Regulation No 844/2012
Hazard Classes and CategoriesAcute Tox. 4 (15.1%)

Safety data

PPE
dust mask type N95 (US), Eyeshields, Gloves
wgk
3
ridadr
2811
hs_code
29333999
risk_code
36/37/38
Signal word
Warning

Chemistry & industry

Applications · 4 items

Description4-Amino-2-chloropyridine is an important pharmaceutical and pesticide intermediate. It can synthesize N-(2-chloro-4-pyridyl)urea regulators that promote plant growth. It is also a key substance in the synthesis of KT-30 (Forchlorfenuron, IUPAC name N-(2-chloro-4-pyridyl)-N'-phenylurea). KT-30 is a highly active cytokinin, which has the biological activity of promoting tissue growth, promoting bud development and green preservation; it has an effect of increasing yield on apple, pear, grape, peach and other fruit crops. 4-Amino-2-chloropyridine itself can also be used as a pesticide alone, and has high activity against various pathogens such as rust, powdery mildew, rice blast, and apple downy mildew. 4-Amino-2-chloropyridine and its pharmaceutical and pesticide intermediates have the advantages of high biological activity, low toxicity, long-lasting period and easy degradation in the environment, so they have broad application prospects in agricultural production.

UsesAn aminopyridine derivative with potential herbicidal activity.

Uses4-Amino-2-chloropyridine may be used in the preparation of:3-deazacytosine7-substituted 1-alky-1,4-dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acids1,6-naphthyridines

General Description4-Amino-2-chloropyridine is a chloroaminoheterocyclic compound. It readily undergoes Suzuki-Miyaura coupling with phenylboronic acid.

Suppliers100 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
北京安司莫森技术有限公司010-82954736 13391601435 · [email protected]
韶远科技(上海)有限公司021-50795510 4000665055 · [email protected]

Additional notes

DefinitionChEBI: 4-Amino-2-chloropyridine is an aminopyridine.

Related reactions

124 records

Compound notes

Loading…