alpha-D-lactose

HCID 84571CAS 10039-26-6
Substructure searchFind similar structures

Basic information

Standard SMILES
OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
InChIKey
GUBGYTABKSRVRQ-XLOQQCSPSA-N
Molecular formula
C12H22O11
Average molar mass
342.3 g/mol
Monoisotopic mass
342.11621152

Overview

Alpha-lactose is the alpha-anomer of lactose.

Names & identifiers

Preferred name
alpha-D-lactose
IUPAC
(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
English name
Lactose, monohydrate
Molecular formula
C12H22O11.H2O
Molecular weight
360.31

Names & synonyms

alpha-lactose14641-93-1alpha-D-lactosealpha-D-Glucopyranose, 4-O-beta-D-galactopyranosyl-MJF4JAT10B(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triolCHEBI:36219DTXSID50873004beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-(((2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl)oxy)oxane-3,4,5-triol(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-((2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl)oxyoxane-3,4,5-triol
Show more names
L-CYSTEINE HYDROCHLORIDEMILK SUGARMonohydrate LactoseLACTOSE BPLACTOSUM MONOHYDRICUMMILK SUGAR MONOHYDRATELACTOSE MONOHYDRATE USPAROSE 25Ph.Eur.,USPLACTOSE 1H2O
RefChem:555805GlyTouCan:G88362QRDTXCID30820516G88362QR238-691-8(2S,3R,4R,5S,6R)-6-(Hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol4-O-beta-D-Galactopyranosyl-alpha-D-glucopyranoseA-MILK SUGAR

Database identifiers

CAS
10039-26-6、14641-93-1、63-42-3、64044-51-5
PubChem CID
84571
DTXSID
DTXSID50873004
ChEBI
CHEBI:36219
UNII
MJF4JAT10B
EC Number
238-691-8
Nikkaji
J241.337J

Properties

Computed structural properties

XLogP
-4.7
Topological polar surface area
190 Ų
Hydrogen bond donors
8
Hydrogen bond acceptors
11
Rotatable bonds
4
Heavy atoms
23

Experimental & physicochemical properties

Solubility195 mg/mL at 20 °C
Melting Point201 - 202 °C
Physical DescriptionSolid
Collision Cross Section · 2 items

186.3 Ų [M+Li]+ [CCS Type: DT; Method: stepped-field]

178.6 Ų [M+K]+

Physicochemical properties

Melting point
215 °C · ~215 °C (dec.)
Density
500 kg/m3 · 500kg/m3
bulk density
500 kg/m3 · 500kg/m3
storage temp.
room temp
solubility
2 O: · H2O: 0.5 M at 20 °C, clear, colorless
form
Solid

Safety & regulation

Hazard information

Regulatory Information · 3 items

Chemical: D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate

.alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Lactose monohydrate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate: Human health tier I assessment

Safety data

F
3
wgk
3
Storage Class
11 - Combustible Solids
Autoignition Temperature
390°C

Chemistry & industry

Pharmacology

Tissue LocationsBladder
Cellular LocationsCytoplasm
Metabolite PathwaysCongenital disorder of glycosylation CDG-IId

Uses & manufacturing

General Manufacturing Information.alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-: ACTIVE

Applications

UsesExcipient.

Upstream & downstream products

Upstream raw materials

Suppliers50 total

銘瑞集團有限公司17318633522 · [email protected]
山东泰诚生物科技有限公司18769832557 18769832557 · [email protected]
上海纯优生物科技有限公司18302135232 18302135232 · [email protected]
Shaanxi LonierHerb Bio Technology Co Ltd+86-86-+86-86-029-87551862 15002946897 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

Related reactions

5 records
New reaction record

Linked notes

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