Magnesium Acetate

HCID 8896
NotesReactions
Substructure searchFind similar structures

Basic information

CAS
142-72-3
Standard SMILES
CC(=O)[O-].CC(=O)[O-].[Mg+2]
InChIKey
UEGPKNKPLBYCNK-UHFFFAOYSA-L
Molecular formula
C4H6O4Mg
Average molar mass
142.39 g/mol
Monoisotopic mass
142.01165037

Overview

Magnesium acetate is the magnesium salt of acetic acid. It is functionally related to an acetic acid.

Names & identifiers

Preferred name
Magnesium Acetate
IUPAC
magnesium diacetate
English name
Magnesium acetate
Molecular formula
C4H6MgO4
Molecular weight
142.39

Names & synonyms

Magnesium acetate142-72-3Magnesium diacetateACETIC ACID, MAGNESIUM SALTMagnesium di(acetate)Mg AcetateAcetic acid magnesium saltMagnesium acetate anhydrousAcetic acid, magnesium salt (2:1)Mg(II) acetateMagnesium acetate, mg(oac)2DTXSID7027097
Show more names
Nu-MagC4H6MgO4Cromosan*MagnesiumAcetateBpacetatedemagnesiummagnesiumdiacetate
NSC-757980E95JZY48KDTXCID207097CHEBI:62964NSC75798RefChem:800477205-554-9Cromosan

Database identifiers

CAS
142-72-3
PubChem CID
8896
DTXSID
DTXSID7027097
ChEMBL
CHEMBL1200691
ChEBI
CHEBI:62964
UNII
0E95JZY48K
EC Number
205-554-9
Nikkaji
J43.168K

Properties

Computed structural properties

Topological polar surface area
80.3 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
4
Rotatable bonds
0
Heavy atoms
9

Experimental & physicochemical properties

Chemical ClassesMetals -> Organic Acids, Metal Salts
Cosmetics · 2 items

Cosmetic ingredients (Magnesium Acetate) -> CIR (Cosmetic Ingredient Review)

Buffering

Human Drugs · 2 items

FDA approved drugs -> Active ingredient

FDA approved drugs -> Active ingredient

Physical Description · 2 items

Liquid; Large Crystals

Tetrahydrate: Colorless or white deliquescent solid; [Merck Index] White hygroscopic crystals with a mild odor of acetic acid; [Mallinckrodt Baker MSDS]

Physicochemical properties

Melting point
72 · 72-75 °C(lit.)
Density
1.5 · 1.5000
refractive index
20 · n20/D 1.358
solubility
2 O: · H2O: 1 M at 20 °C, clear, colorless
form
Liquid
pka
4.756 · 4.756[at 20 ℃]

Safety & regulation

GHS classification

GHS Classification · 3 items

This chemical does not meet GHS hazard criteria for 99.5% (2416 of 2427) of all reports.

Not Classified

Aggregated GHS information provided per 2427 reports by companies from 3 notifications to the ECHA C&L Inventory.

Hazard information

Regulatory Information · 4 items

Chemical: Acetic acid, magnesium salt

Acetic acid, magnesium salt (2:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, magnesium salt (2:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 10-10-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13613

Acetic acid, magnesium salt: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Acetic acid, magnesium salt: Human health tier I assessment
Hazards Summary · 1 item

Members of the acetic acid and salts subcategory demonstrate low acute oral, dermal, and inhalation toxicity; Hyperplasia of the esophagus and forestomach in repeated-dose oral studies of rats; Increased spleen and kidney weights and signs of kidney injury in continuous inhalation studies at 23-31 ppm/day (60-80 mg/m3/day); No maternal or developmental toxicity in mice, rats, or rabbits in oral studies (doses up to 1,600 mg/kg/day); No evidence of mutagenicity; [EPA ChAMP: Hazard Characterization] May cause irritation; [Mallinckrodt Baker MSDS] See Sodium acetate.

EPA Safer ChemicalChemical: Magnesium acetate
Hazard Classes and CategoriesNot Classified

Safety & protection

Protective Action Criteria (PAC) · 3 items

26 [mg/m3]

280 [mg/m3]

1700 [mg/m3]

Toxicology

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Safety data

F
3
PPE
Eyeshields, Gloves
wgk
3
tsca
TSCA listed
rtecs
AI5600000
Signal word
Warning

Chemistry & industry

Uses & manufacturing

Uses · 2 items

CIR ingredient: Magnesium Acetate

Used as a buffer and to detect sodium; [Merck Index] Used as a catalyst for sulfuric acid; [EPA OHM/TADS] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

U.S. Production2023: 10,000,000 - <50,000,000 lb
Consumer UsesOther
Industry UsesDye
Use Classification · 4 items

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Food Additives -> FOOD_ADDITIVE -> JECFA Functional Classes

Cosmetics -> Buffering

General Manufacturing Information · 2 items

All Other Basic Inorganic Chemical Manufacturing

Acetic acid, magnesium salt (2:1): ACTIVE

Applications · 5 items

UsesMagnesium acetate is used in the manufacture of rayon fiber for cigarette filters; and as a fixative for dyes in textile printing. It also is used as an antiseptic and disinfectant.

DescriptionAnhydrous Magnesium Acetate has the chemical formula Mg(CH3COO)2 and in its hydrous form, Magnesium Acetate Tetrahydrate, it has the chemical formula Mg(CH3COO)2.4H2O. In this compound the magnesium metal has an oxidation state of 2+. Magnesium acetate is the magnesium salt of acetic acid.It is deliquescent and upon heating, it decomposes to form magnesium oxide.Magnesium acetate is commonly used as a source of magnesium or as a chemical reagent.

UsesDye fixative in textile printing, deodorant, disinfectant, and antiseptic. Magnesium acetate is used in chemistry and molecular biology as a reagent and a source of magnesium. Magnesium has a variety of biological roles in enzymology, cell membrane and wall structural integrity, muscle cell physiology, and nucleic acid structure.Magnesium is an essential co-factor in many enzymes, including deoxyribonuclease (DNase), the restriction enzymes EcoR I and EcoR V, and Ribonuclease H. Magnesium also stabilizes polymeric nucleic acids such as transfer RNA and ribozymes. Magnesium acetate has been widely used in the crystallization of proteins. A protocol for the separation of MB and BB isoenzymes of creatine kinase and the LD1 isoenzyme of lactate dehydrogenase that involves elution with magnesium acetate has been published.

UsesThe largest use for magnesium acetate is in the production of rayon fiber, which is used for cigarette filter tow. Magnesium acetate also has uses as a dye fixative in textile printing, as a deodorant, disinfectant, an antiseptic in medicine, and as a reagent chemical.

UsesMagnesium acetate is used in molecular biology applications such as batch in vitro transcription of RNA and the crystallization of transcription factor:DNA complexes and proteins via the sitting-drop vapor-diffusion method. Also used as a buffer and to detect sodium and as a catalyst for sulfuric acid.

Preparation methods · 1 item

PreparationMagnesium acetate is prepared by treating magnesium oxide with acetic acid. Magnesium oxide reacts with concentrated acetic acid in boiling ethyl acetate to produce the alpha form of anhydrous magnesium acetate. The beta form is obtained by treating the oxide with 5–6% acetic acid. In slightly hydrated isobutyl alcohol medium the product is a monohydrate, Mg(OOCCH3)2•H2O. In aqueous solution magnesium acetate crystallizes as a tetrahydrate, the commercial product. The tetrahydrate dehydrates to anhydrous salt at 134°C.

Upstream & downstream products

Suppliers100 total

湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
天津市光复科技发展有限公司022-85689490 13132141716 · [email protected]

Additional notes

DefinitionChEBI: The magnesium salt of acetic acid.

Related reactions

28 records
New reaction record

Compound notes

Loading…