1-Methyl-2-piperidinemethanol (HCID 89394)

Names & identifiers

Preferred name: 1-Methyl-2-piperidinemethanol
IUPAC: (1-methylpiperidin-2-yl)methanol
English name: 1-Methyl-2-piperidinemethanol
Molecular formula: C7H15NO
Molecular weight: 129.2

Names & synonyms

1-Methyl-2-piperidinemethanol20845-34-52-Piperidinemethanol, 1-methyl-NSC 45464DTXSID301307492EINECS 244-078-6RefChem:434080DTXCID908721572-(Hydroxymethyl)-N-methylpiperidine244-078-6(1-methylpiperidin-2-yl)methanol1-Methylpiperidine-2-methanol

Show more names

2-(Hydroxymethyl)Methyl-2-piperidineMethaN-Methylpiperidine-2-carbinolN-Methyl-2-piperidineMethanolN-Methylpiperidine-2-methanolN-Methyl-2-piperidinecarbinol

MFCD000064942-Hydroxymethyl-1-methylpiperidine(1-methyl-2-piperidyl)methanol1-Methyl-2-hydroxymethylpiperidine(1-methyl-2-piperidyl)methan-1-ol2-hydroxymethyl-N-methylpiperidineNSC454641-methyl-2piperidinemethanol

Database identifiers

CAS: 20845-34-5
PubChem CID: 89394
DTXSID: DTXSID301307492
EC Number: 244-078-6
Nikkaji: J149.933E

Properties

Computed structural properties

XLogP: 0.5
Topological polar surface area: 23.5 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 2
Rotatable bonds: 1
Heavy atoms: 9
Formal charge: 0
Complexity: 85

Physicochemical properties

Boiling point: 79 · 79-80 °C/7 mmHg (lit.)
Density: 0.984 g/mL · 0.984 g/mL at 25 °C (lit.)
refractive index: 20 · n20/D 1.4823(lit.)
Flash point: 178 °F · 178 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Dichloromethane, Methanol
form: Liquid
pka: 15.08 · 15.08±0.10(Predicted)
color: Clear brown
BRN: 103612 · 103612
InChI: InChI=1S/C7H15NO/c1-8-5-3-2-4-7(8)6-9/h7,9H,2-6H2,1H3
InChIKey: HXXJMMLIEYAFOZ-UHFFFAOYSA-N
SMILES: N1(C)CCCCC1CO
CAS DataBase Reference: 20845 · 20845-34-5(CAS DataBase Reference)
NIST Chemistry Reference: 1 · 1-Methyl-2-piperidinemethanol(20845-34-5)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 227 · H227-H315-H319-H335
Precautionary statements: 210 e-P261-P280a-P305+P351+P338-P405-P501a · P210e-P261-P280a-P305+P351+P338-P405-P501a
Hazard Codes: Xi
Risk Statements: 36 · 36/37/38
Safety Statements: 24 · 24/25
WGK Germany: 3 · 3
HS Code: 29333999 · 29333999

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H227 (16.7%): Combustible liquid [Warning Flammable liquids]

P210, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information2-(Hydroxymethyl)-N-methylpiperidine: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesFlam. Liq. 4 (16.7%)

Safety data

wgk: 3
hs_code: 29333999
risk_code: 36/37/38
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi
safety_code: 24/25
Hazard statements: H227-H315-H319-H335
Precautionary statements: P210e-P261-P280a-P305+P351+P338-P405-P501a

Chemistry & industry

Applications · 3 items

Uses1-Methyl-2-piperidinemethanol is used as a reagent to synthesize phenylpyridone derivatives, compounds that act as anti-obesity agents in mice.

Uses1-Methyl-2-piperidinemethanol can be used in the preparation of substances for treatment of dermatological conditions and skin protection.

General DescriptionThe standard molar energy of combustion of 1-Methyl-2-piperidinemethanol has been studied.