Ethylenediamine Dihydrochloride

HCID 9521CAS 333-18-6
Substructure searchFind similar structures

Basic information

Standard SMILES
Cl.Cl.NCCN
InChIKey
OHHBFEVZJLBKEH-UHFFFAOYSA-N
Molecular formula
C2H10Cl2N2
Average molar mass
133.02 g/mol
Monoisotopic mass
132.0221037

Names & identifiers

Preferred name
Ethylenediamine Dihydrochloride
IUPAC
ethane-1,2-diamine;dihydrochloride
English name
Ethylenediamine dihydrochloride
Molecular formula
C2H10Cl2N2
Molecular weight
133.02

Names & synonyms

Ethylenediamine dihydrochloride333-18-6Ethylenediammonium dichloride1,2-Diaminoethane dihydrochlorideEthylenediammonium chlorideDimethylenediamine dihydrochlorideEthylenediamine, dihydrochlorideCHEBI:5362691WQV43244DTXSID5043920NSC-163962RefChem:139151
Show more names
ETHYLENEDIAMINE 2HCLEthylenediaminehydrochlorideEthylenediamine dihyenediamine dihydrochLETHYLENEDIAMINE DI HCLEthylenediamine dichloride
DTXCID3023920206-369-6ethane-1,2-diamine dihydrochlorideChlor-ethamine1,2-Ethanediamine, dihydrochlorideethane-1,2-diamine;dihydrochlorideMFCD00012524Dimethylenediamine diydrochloride

Database identifiers

CAS
333-18-6
PubChem CID
9521
DTXSID
DTXSID5043920
ChEBI
CHEBI:53626
UNII
91WQV43244
EC Number
206-369-6

Properties

Computed structural properties

Topological polar surface area
52 Ų
Hydrogen bond donors
4
Hydrogen bond acceptors
2
Rotatable bonds
1
Heavy atoms
6

Experimental & physicochemical properties

Physical DescriptionWhite crystalline solid; Hygroscopic; [Sigma-Aldrich MSDS]

Physicochemical properties

Melting point
300 °C · >300 °C(lit.)
Density
1.46 g/cm3 · 1.46 g/cm3
bulk density
650 kg/m3 · 650kg/m3
storage temp.
30 °C · Store below +30°C.
solubility
100 mg/mL, · water: soluble100mg/mL, clear, colorless to very faintly yellow
form
Crystalline Powder

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H302 (94.4%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (93%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (93%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (93%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H334 (88.7%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]；H335 (88.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P233, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 71 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory Information · 2 items

Chemical: 1,2-Ethanediamine, dihydrochloride

Ethylenediammonium dichloride: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1 item

Causes allergic dermatitis in 48-hr constant dermal studies of humans; [RTECS] A skin and strong eye irritant; May cause skin and respiratory sensitization; Harmful by ingestion; Reproductive and developmental toxicity observed in experimental animals; [Sigma-Aldrich MSDS] See Ethylenediamine.

Hazard Classes and CategoriesAcute Tox. 4 (94.4%)；Skin Irrit. 2 (93%)；Skin Sens. 1 (93%)；Eye Irrit. 2A (93%)；Resp. Sens. 1 (88.7%)；STOT SE 3 (88.7%)

Safety & protection

Protective Action Criteria (PAC) · 3 items

2.7 [mg/m3]

29 [mg/m3]

180 [mg/m3]

Toxicology

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.；Asthma - Reversible bronchoconstriction (narrowing of bronchioles) initiated by the inhalation of irritating or allergenic agents.

Regulatory information

Regulatory Information · 2 items

Chemical: 1,2-Ethanediamine, dihydrochloride

Ethylenediammonium dichloride: Does not have an individual approval but may be used under an appropriate group standard

Safety data

wgk
2
tsca
TSCA listed
rtecs
KV3850000
hs_code
29212100
Toxicity
LD50 orally in Rabbit: 3250 mg/kg LD50 dermal Rabbit > 2000 mg/kg
risk_code
22-36/37/38-42/43

Chemistry & industry

Uses & manufacturing

General Manufacturing Information1,2-Ethanediamine, hydrochloride (1:2): ACTIVE
Applications · 2 items

UsesEthylenediamine dihydrochloride is used as stabilizer in steroid creams and rubber latex; inhibitor in antifreeze solutions and cooling fluids; in floor-polish remover; in nystatin cream and aminophylline; epoxy-curing agent; accelerator in color development baths in photography; in veterinary preparations; in electroplating and electrophoretic gels, dyes, fungicides, insecticides, synthetic waxes, textile lubricants, and eye and nose drops; solvent for casein, albumin, shellac.

UsesEthylenediamine dihydrochloride was used in modified ethylenediamine condensation method for fluorimetric determination of catecholamines. It was used to investigate the luminescence properties of complexes of EuIII and TbIII with ethylenediamine. It was used in the synthesis of 1,3,5-tris(4,5-dihydro-1H-imidazol-2-yl)benzene.

Upstream & downstream products

Upstream raw materials

Downstream products

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
河南萨克斯生物科技有限公司13803717460 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Additional notes

DefinitionChEBI: A hydrochloride that is the dihydrochloride of ethylenediamine.

Related reactions

3 records
New reaction record

Linked notes

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