Ethylenediamine Dihydrochloride
Basic information
- CAS
333-18-6- Standard SMILES
Cl.Cl.NCCN- InChIKey
OHHBFEVZJLBKEH-UHFFFAOYSA-N- Molecular formula
- C2H8N2.2ClH
- Average molar mass
- 133.02 g/mol
- Monoisotopic mass
- 132.0221037
Overview
Ethylenediamine dihydrochloride is a hydrochloride that is the dihydrochloride of ethylenediamine. It has a role as an allergen. It is functionally related to an ethylenediamine.
Names & identifiers
- Preferred name
- Ethylenediamine Dihydrochloride
- IUPAC
- ethane-1,2-diamine;dihydrochloride
- English name
- Ethylenediamine dihydrochloride
- Molecular formula
- C2H10Cl2N2
- Molecular weight
- 133.02
Names & synonyms
Ethylenediamine dihydrochloride333-18-6Ethylenediammonium dichloride1,2-Diaminoethane dihydrochlorideEthylenediammonium chlorideDimethylenediamine dihydrochlorideEthylenediamine, dihydrochlorideCHEBI:5362691WQV43244DTXSID5043920NSC-163962RefChem:139151
Show more names
ETHYLENEDIAMINE 2HCLEthylenediaminehydrochlorideEthylenediamine dihyenediamine dihydrochLETHYLENEDIAMINE DI HCLEthylenediamine dichloride
DTXCID3023920206-369-6ethane-1,2-diamine dihydrochlorideChlor-ethamine1,2-Ethanediamine, dihydrochlorideDimethylenediamine diydrochlorideethane-1,2-diamine;dihydrochlorideMFCD00012524
Database identifiers
- CAS
333-18-6- PubChem CID
- 9521
- DTXSID
DTXSID5043920- ChEBI
CHEBI:53626- UNII
- 91WQV43244
- EC Number
- 206-369-6
Properties
Computed structural properties
- Topological polar surface area
- 52 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 1
- Heavy atoms
- 6
- Formal charge
- 0
- Complexity
- 6
Experimental & physicochemical properties
Chemical ClassesNitrogen Compounds -> Amines, Aliphatic
Physical DescriptionWhite crystalline solid; Hygroscopic; [Sigma-Aldrich MSDS]
Physicochemical properties
- Melting point
- 300 °C · >300 °C(lit.)
- Density
- 1.46 g/cm3 · 1.46 g/cm3
- bulk density
- 650 kg/m3 · 650kg/m3
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- 100 mg/mL, · water: soluble100mg/mL, clear, colorless to very faintly yellow
- form
- Crystalline Powder
- color
- White to off-white
- PH
- 5 · 5 (100g/l, H2O, 20℃)
- Water Solubility
- 300 g/L · 300 g/L (20 ºC)
- Sensitive
- Hygroscopic
- BRN
- 3665235 · 3665235
- Stability
- Stable. Incompatible with strong oxidizing agents.
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (94.4%): Harmful if swallowed [Warning Acute toxicity, oral]
P233, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 71 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: 1,2-Ethanediamine, dihydrochloride
Ethylenediammonium dichloride: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Causes allergic dermatitis in 48-hr constant dermal studies of humans; [RTECS] A skin and strong eye irritant; May cause skin and respiratory sensitization; Harmful by ingestion; Reproductive and developmental toxicity observed in experimental animals; [Sigma-Aldrich MSDS] See Ethylenediamine.
Hazard Classes and CategoriesAcute Tox. 4 (94.4%)
Safety & protection
Protective Action Criteria (PAC)
2.7 [mg/m3]
29 [mg/m3]
180 [mg/m3]
Toxicology
Chemistry & industry
Uses & manufacturing
General Manufacturing Information1,2-Ethanediamine, hydrochloride (1:2): ACTIVE
Applications
UsesEthylenediamine dihydrochloride is used as stabilizer in steroid creams and rubber latex; inhibitor in antifreeze solutions and cooling fluids; in floor-polish remover; in nystatin cream and aminophylline; epoxy-curing agent; accelerator in color development baths in photography; in veterinary preparations; in electroplating and electrophoretic gels, dyes, fungicides, insecticides, synthetic waxes, textile lubricants, and eye and nose drops; solvent for casein, albumin, shellac.
UsesEthylenediamine dihydrochloride was used in modified ethylenediamine condensation method for fluorimetric determination of catecholamines. It was used to investigate the luminescence properties of complexes of EuIII and TbIII with ethylenediamine. It was used in the synthesis of 1,3,5-tris(4,5-dihydro-1H-imidazol-2-yl)benzene.
Upstream & downstream products
Upstream raw materials
Downstream products
Additional notes
DefinitionChEBI: A hydrochloride that is the dihydrochloride of ethylenediamine.
Related reactions
3 records
Compound notes
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