2-Fluoro-6-methylpyridine (HCID 96090)

Names & identifiers

Preferred name: 2-Fluoro-6-methylpyridine
IUPAC: 2-fluoro-6-methylpyridine
English name: 2-Fluoro-6-methylpyridine
Molecular formula: C6H6FN
Molecular weight: 111.12

Names & synonyms

2-Fluoro-6-methylpyridine407-22-7Pyridine, 2-fluoro-6-methyl-EINECS 206-980-8DTXSID50193673NSC 51590RefChem:87121DTXCID90116164206-980-8UDMNVTJFUISBFD-UHFFFAOYSA-N2-fluoro-6-picoline6-Fluoro-2-picoline

Show more names

6-me6-methyl-2-fluoropyridine2-Fluoro-6-methylpyridine98%2-Fluoro-6-methylpyridine>2-FLUORO-6-METHYLPYRIDINE 98%2-Bromo-3-methyl-6-nitropyridine

2-fluoro-6-methyl-pyridineMFCD000412262-methyl-6-fluoro-pyridineAB01860PS-9256SY014114EN300-865496-fluoro-2-methylpyridine

Database identifiers

CAS: 407-22-7
PubChem CID: 96090
DTXSID: DTXSID50193673
EC Number: 206-980-8
Nikkaji: J213.666J

Properties

Computed structural properties

XLogP: 1.2
Topological polar surface area: 12.9 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 2
Rotatable bonds: 0
Heavy atoms: 8
Formal charge: 0
Complexity: 74.9

Physicochemical properties

Boiling point: 140 · 140-141 °C (lit.)
Density: 1.077 g/mL · 1.077 g/mL at 25 °C (lit.)
refractive index: 20 · n20/D 1.47(lit.)
Flash point: 152 °F · 152 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: clear liquid
pka: 0.29 · 0.29±0.10(Predicted)
color: Colorless to Light orange to Yellow
Specific Gravity: 1.07 · 1.07
BRN: 107084 · 107084
InChI: 1S/C6H6FN/c1-5-3-2-4-6(7)8-5/h2-4H,1H3
InChIKey: UDMNVTJFUISBFD-UHFFFAOYSA-N
SMILES: Cc1cccc(F)n1
CAS DataBase Reference: 407 · 407-22-7(CAS DataBase Reference)
NIST Chemistry Reference: 2 · 2-Fluoro-6-methylpyridine(407-22-7)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 315 · H315-H319-H335
Precautionary statements: 261 · P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs: Respiratory system
PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: Xi,F
Risk Statements: 36 · 36/37/38
Safety Statements: 26 · 26-36
RIDADR: 1993 · 1993
WGK Germany: 3 · 3
Hazard Note: Flammable/Irritant
HazardClass: IRRITANT
HS Code: 29333990 · 29333990
Storage Class: 10 · 10 - Combustible liquids
Hazard Classifications: 2 Skin · Eye Irrit. 2Skin Irrit. 2STOT SE 3

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 50 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Safety data

PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 3
ridadr: 1993
hs_code: 29333990
risk_code: 36/37/38
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi,F
hazard_note: Flammable/Irritant
safety_code: 26-36
hazard_class: IRRITANT
Storage Class: 10 - Combustible liquids
target organs: Respiratory system
Hazard statements: H315-H319-H335
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338

Chemistry & industry

Applications · 2 items

Uses2-Fluoro-6-methylpyridine may be used in the preparation of:2-fluoro-6-pyridinecarboxylic acid2,2′-[1-(6-methylpyridin-2-yl)ethane-1,1-diyl]dipyridine2-fluoropyridine-6-aldoxime2-fluoro-6-(dibromomethyl)pyridine

General Description2-Fluoro-6-methylpyridine, also known as 2-fluoro-6-picoline, can be prepared via diazotization of 2-amino-6-methylpyridine in hydrogen fluoride containing 40% pyridine solution. The effect of substituents on spectral properties of 2-fluoro-6-methylpyridine has been investigated based on 13C NMR, UV and IR spectral data.